Last reviewed · How we verify
NCT04569643
Periodic Limb Movement Syndrome in Patients With Cerebral Small Vessel Disease.
trial testing Actigraphy in Periodic Limb Movement Disorder in 76 participants. Status unknown.
30 April 2022
Quick facts
| Lead sponsor | I.M. Sechenov First Moscow State Medical University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 76 |
| Start date | 1 December 2020 |
| Primary completion | 30 April 2022 |
| Estimated completion | 31 August 2022 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- Actigraphy
- Cardiorespiratory monitoring
- Neuroimaging
- Assessment of cognitive function
- Sleep quality and mood questionnaires
Conditions studied
- Periodic Limb Movement Disorder — all drugs for Periodic Limb Movement Disorder →
- Cerebral Small Vessel Diseases — all drugs for Cerebral Small Vessel Diseases →
- Cognitive Dysfunction — all drugs for Cognitive Dysfunction →
Sponsor
I.M. Sechenov First Moscow State Medical University
Who can join
Adults 60 to 75, any sex, with Periodic Limb Movement Disorder or Cerebral Small Vessel Diseases. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patients from 60 to 75 years old diagnosed with cerebral small vessel disease with no history of symptomatic stroke, brain tumor, traumatic brain injury, seizures and neurodegenerative or mental disorder will undergo overnight leg actigraphy and cardiorespiratory monitoring. Those of them with apnea/hypopnea index under 5 will be enrolled. Brain MRI and cognitive assessment will be performed at baseline and in 1-year follow-up, sleep quality will be assessed at baseline with self-reported questionnaires. Progression of cerebral small vessel disease markers and cognitive dysfunction will be compared between patients with high periodic limb movement index (the number of periodic limb movement ≥ 15 per hour of sleep) and controls (periodic limb movement index \< 15/h).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Periodic Limb Movements Syndrome in Patients With Cerebral Small Vessel Disease: Protocol for a Prospective Observational Study.
Spektor E, Fietze I, Poluektov MG. · · 2021 · cited 3× · PMID 34646228 · DOI 10.3389/fneur.2021.700151
Verify or expand the search:
- PubMed search for NCT04569643
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04569643 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by I.M. Sechenov First Moscow State Medical University
- Last refreshed: 21 February 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04569643.
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