Who is sponsoring NCT04553198?

NCT04553198 is sponsored by University of Cincinnati.

What drugs are being tested in NCT04553198?

Interventions in NCT04553198: Backward Locomotion Treadmill Training (BLTT).

What condition does NCT04553198 study?

NCT04553198 studies Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic.

Is NCT04553198 still recruiting?

NCT04553198 is currently completed. Last updated 13 September 2023.

Last reviewed 2023-09-13 · How we verify

NCT04553198: BLT2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery

Completed NA Last updated 13 September 2023

What this trial tests

NA trial testing Backward Locomotion Treadmill Training (BLTT) in Stroke in 44 participants. Completed in 3 January 2023.

Timeline

1 September 2020

Primary endpoint
3 January 2023

3 January 2023

Quick facts

Lead sponsor	University of Cincinnati
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	44
Start date	1 September 2020
Primary completion	3 January 2023
Estimated completion	3 January 2023
Sites	1 location across United States

Drugs / interventions tested

Backward Locomotion Treadmill Training (BLTT)

Conditions studied

Stroke — all drugs for Stroke →
Chronic Stroke — all drugs for Chronic Stroke →
Walking, Difficulty — all drugs for Walking, Difficulty →
Gait, Hemiplegic — all drugs for Gait, Hemiplegic →

Sponsor

University of Cincinnati

Who can join

Adults 18 to 80, any sex, with Stroke or Chronic Stroke. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Despite current walking rehabilitation strategies, the majority of stroke survivors are unable to walking independently in the community and remain at increased risk of falls. Backward treadmill training is a novel training approach used by elite athletes to enhance speed, agility, and balance; however, it is currently unknown how this exercise interacts with the central nervous system or if it could benefit stroke survivors with residual walking impairment. Knowledge gained from this study will likely lead to more effective walking rehabilitation strategies in stroke and related disorders.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Insufficiencies in sensory systems reweighting is associated with walking impairment severity in chronic stroke: an observational cohort study.
Awosika OO, Garver A, Drury C, Sucharew HJ, et al · · 2023 · cited 9× · PMID 38020645 · DOI 10.3389/fneur.2023.1244657

Verify or expand the search:

Other trials of Backward Locomotion Treadmill Training (BLTT)

Trials testing the same drug.

NCT04721860 — Optimizing Training in Severe Post-Stroke Walking Impairment · NA · completed

Other recruiting trials for Stroke

Currently open trials in the same condition.

NCT06615973 — Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke · recruiting
NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
NCT07356011 — Exoskeleton for Balance · NA · recruiting
NCT07523503 — Unilateral Versus Bilateral Task-specific Training on Motor Impairment, Upper Extremity Function, and Hand Dexterity in · NA · recruiting
NCT06704074 — Virtual Reality Task Oriented Training on Upper Limb Function in Stroke Patients · NA · recruiting

Other University of Cincinnati trials

Trials by the same sponsor.

NCT05605366 — Minocycline In Neurocognitive Outcomes - Sickle Cell Disease · Phase 1 · not yet recruiting
NCT07528638 — Intraoperative Neuromonitoring (IONM) and Bipolar Electrocautery (BE) During Axillary Lymph Node Dissection (ALND) · NA · not yet recruiting
NCT07494890 — Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment · NA · recruiting
NCT07447895 — Early Pelvic Floor Physical Therapy for Women Undergoing Pelvic Radiation for Gynecologic Malignancies · NA · not yet recruiting
NCT07231588 — Oral 5 Strain Probiotic for GI Toxicity Mitigation During Pelvic Radiation · EARLY_PHASE1 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04553198 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Cincinnati
Last refreshed: 13 September 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04553198.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing