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NCT07231588
Oral 5 Strain Probiotic for GI Toxicity Mitigation During Pelvic Radiation
EARLY_PHASE1 trial testing Pendulum Glucose Control (PGC) in Radiation Injuries in 20 participants. Currently enrolling.
29 June 2026
Quick facts
| Lead sponsor | University of Cincinnati |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 20 |
| Start date | 29 January 2026 |
| Primary completion | 29 June 2026 |
| Estimated completion | 29 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Pendulum Glucose Control (PGC) — full drug profile →
Conditions studied
- Radiation Injuries — all drugs for Radiation Injuries →
Sponsor
University of Cincinnati
Who can join
18 and older, any sex, with Radiation Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research is to determine if an oral probiotic, Pendulum Glucose Control (PGC), can be safely given to patients during pelvic radiation therapy (RT). The researchers will study if the probiotics lessen gastrointestinal toxicity during pelvic radiation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07231588
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Trials by the same sponsor.
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- NCT07447895 — Early Pelvic Floor Physical Therapy for Women Undergoing Pelvic Radiation for Gynecologic Malignancies · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07231588 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Cincinnati
- Last refreshed: 5 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07231588.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing