Last reviewed · How we verify
NCT04544631
VR for Pediatric Burn Dressing Changes
NA trial testing Virtual reality game as adjunctive pain management tool in Pain in 90 participants. Completed in 3 March 2019.
31 January 2019
Quick facts
| Lead sponsor | Nationwide Children's Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 1 December 2016 |
| Primary completion | 31 January 2019 |
| Estimated completion | 3 March 2019 |
Drugs / interventions tested
- Virtual reality game as adjunctive pain management tool
Conditions studied
Sponsor
Nationwide Children's Hospital
Who can join
Adults 6 to 17, any sex, with Pain or Burns. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study evaluated a smart phone virtual reality (VR) to manage pediatric burn dressing pain. A randomized controlled trial was conducted among 90 patients (6-17 years). Active VR participants played the game, passive VR group were immersed in the same VR without interactions, and a standard care group served as the control. One researcher administered VR and observed pain while another researcher administered post-trial survey that measured child's perceived pain and VR experience. Nurses were asked to report the clinical utility.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Efficacy of Smartphone Active and Passive Virtual Reality Distraction vs Standard Care on Burn Pain Among Pediatric Patients: A Randomized Clinical Trial.
Xiang H, Shen J, Wheeler KK, Patterson J, et al · · 2021 · cited 80× · PMID 34152420 · DOI 10.1001/jamanetworkopen.2021.12082 -
Features of virtual reality impact effectiveness of VR pain alleviation therapeutics in pediatric burn patients: A randomized clinical trial.
Jain S, Armstrong M, Luna J, Thakkar RK, et al · · 2024 · cited 12× · PMID 38271320 · DOI 10.1371/journal.pdig.0000440 -
Age and Sex Differences of Virtual Reality Pain Alleviation Therapeutic During Pediatric Burn Care: A Randomized Clinical Trial.
Jones K, Armstrong M, Luna J, Thakkar RK, et al · · 2024 · cited 1× · PMID 39091668 · DOI 10.1089/jmxr.2024.0004
Verify or expand the search:
- PubMed search for NCT04544631
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Nationwide Children's Hospital trials
Trials by the same sponsor.
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- NCT07026942 — Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML · Phase 1, PHASE2 · not yet recruiting
- NCT06795126 — Little NIRVANA for Pediatric Pain and Anxiety · NA · enrolling by invitation
- NCT06854991 — Healthy Children and Virtual Reality Mediation of Simulated Pain · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04544631 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nationwide Children's Hospital
- Last refreshed: 23 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04544631.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing