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NCT04541732
Postoperative Analgesia of Quadratus Lumborum Block Versus Epidural Block After Major Abdominal Surgeries
NA trial testing Thoracic epidural block in Elective Major Abdominal Surgery in 80 participants. Completed in 6 May 2019.
9 April 2019
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 80 |
| Start date | 1 January 2019 |
| Primary completion | 9 April 2019 |
| Estimated completion | 6 May 2019 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Thoracic epidural block — full drug profile →
- Ultrasound-guided bilateral quadratus lumborum block
- Induction of general anaesthesia with propofol — full drug profile →
- Muscle Relaxant — full drug profile →
- Maintenance of general anaesthesia — full drug profile →
Conditions studied
- Elective Major Abdominal Surgery — all drugs for Elective Major Abdominal Surgery →
Sponsor
Mansoura University
Who can join
Adults 20 to 65, any sex, with Elective Major Abdominal Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Acute postoperative pain is an important issue after major abdominal surgeries for which different analgesic modalities have been tried. Epidural analgesia is the recommended technique to relieve pain after major abdominal surgeries owing to the proved superior analgesia, reduction of opioid-related side effects as nausea, vomiting, pruritis and sedation, earlier recovery of bowel function and earlier ability for postoperative mobility. However, it is not without complications. Quadratus lumborum block is an ultrasound-guided block that provides patients with both visceral and somatic blockade. It lessens the potential risks associated with neuraxial techniques, so it may represent a novel alternative approach for analgesia after major abdominal surgeries.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04541732
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Thoracic epidural block
Trials testing the same drug.
- NCT06974643 — Thoracic Epidural Anesthesia Versus Paravertebral Block for Awake Thoracotomy · NA · recruiting
- NCT06884852 — Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastect · NA · recruiting
- NCT03677856 — The Effectiveness of ThOracic Epidural and Paravertebral Blockade In Reducing Chronic Post- Thoracotomy Pain: 2 · NA · unknown
- NCT03087604 — Loss of Resistance, w/wo Stimulation, For Epidural Placement · Phase 4 · completed
Other recruiting trials for Elective Major Abdominal Surgery
Currently open trials in the same condition.
- NCT07303855 — Effectiveness of Goal-Directed Fluid Therapy Guided by Cardiac Index Versus Central Venous Pressure in Major Abdominal S · NA · recruiting
- NCT06182215 — PostoperAtive Neurocognitive Dysfunction After Major AbdomiNal Surgery (PANDAMAN) · recruiting
Other Mansoura University trials
Trials by the same sponsor.
- NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04541732 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 9 September 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04541732.
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