Last reviewed · How we verify
NCT04541602: NMCiCIP
Detection of Neuromuscular Complications in Critically Ill Patients
trial in Critical Illness in 5 participants. Terminated before completion.
8 December 2024
Quick facts
| Lead sponsor | University of Rostock |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 5 |
| Start date | 1 September 2020 |
| Primary completion | 8 December 2024 |
| Estimated completion | 8 December 2024 |
| Sites | 1 location across Germany |
Conditions studied
- Critical Illness — all drugs for Critical Illness →
- Dysphagia — all drugs for Dysphagia →
- Intensive Care Unit Acquired Weakness — all drugs for Intensive Care Unit Acquired Weakness →
- Neuromuscular Diseases — all drugs for Neuromuscular Diseases →
Sponsor
University of Rostock
Who can join
18 and older, any sex, with Critical Illness or Dysphagia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Dysphagia and the intensive care unit-acquired weakness (ICU-AW) are common and outcome-relevant neuromuscular complications in critically ill patients, especially after prolonged mechanical ventilation, sepsis and multi-organ failure. However, the impact of these two complications on the clinical course of critically ill patients needs further investigation. Furthermore, the standard diagnostic procedure to detect and grade the acquired dysphagia using the fiberoptic endoscopic evaluation of swallowing (FEES) and the Medical Research Council sum score (MRC-ss) to detect ICU-AW are time-consuming and strongly dependent on patient compliance. An early and easy-to-use detection of these neuromuscular complications is currently difficult to be achieved in this patient population. Neuromuscular ultrasound (NMUS) and the measurement of neuromuscular damage blood biomarkers became increasingly interesting for clinical researchers in the recent years due to their broad availability and their simple and non-invasive application. However, the value of these new diagnostic tests to evaluate dysphagia and ICU-AW needs to be verified.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04541602
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Critical Illness
Currently open trials in the same condition.
- NCT06189924 — Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients · recruiting
- NCT07418242 — Prognostic Value of Novel Biomarkers on Adverse Renal Outcomes in High-Risk Cardiac Surgery Patients · recruiting
- NCT07101640 — PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysp · Phase 1, PHASE2 · recruiting
- NCT07177183 — Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure · NA · recruiting
- NCT07369258 — Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit · NA · recruiting
Other University of Rostock trials
Trials by the same sponsor.
- NCT06489470 — Strokectomy in Malignant Cerebral Media Infarction · NA · recruiting
- NCT06175429 — Prognostic Value of Exhaled Isoprene Levels for Morbidity and Functional Outcome in Cardiosurgical Patients · unknown
- NCT04972617 — Characterization of the Efficacy of Furosemide Depending on Albumin Function · completed
- NCT06318208 — Pulmonary Function in Non-hospitalized Adults and Children After Mild COVID-19 · completed
- NCT05885620 — SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04541602 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Rostock
- Last refreshed: 12 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04541602.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing