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NCT04537455
Non-invasive Mapping Using Ultra-high Frequency Electrocardiography
NA trial testing Ultra-high frequency electrocardiography in Left Bundle-Branch Block in 30 participants. Completed in 10 March 2024.
10 December 2023
Quick facts
| Lead sponsor | Imperial College London |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 30 |
| Start date | 1 October 2019 |
| Primary completion | 10 December 2023 |
| Estimated completion | 10 March 2024 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- Ultra-high frequency electrocardiography
Conditions studied
- Left Bundle-Branch Block — all drugs for Left Bundle-Branch Block →
- Right Bundle-Branch Block — all drugs for Right Bundle-Branch Block →
- Non-Specific Intraventricular Conduction Defect — all drugs for Non-Specific Intraventricular Conduction Defect →
Sponsor
Imperial College London
Who can join
Adults 18 to 100, any sex, with Left Bundle-Branch Block or Right Bundle-Branch Block. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cardiac electrical mapping is an important tool that allows doctors to study the electrical activity of the heart in detail. Electrical mapping systems used in clinical practice are time consuming, invasive and very costly. Ultra-high frequency electrocardiography is a novel non-invasive cardiac mapping system. Ultra-high frequency electrocardiography (UHF-ECG) can be performed in 10-15 minutes without any risk or discomfort to patients. The aim of this study is to refine this mapping system, verify it against invasive mapping and develop software to bring this novel system into routine clinical use including predicting which patients will respond to cardiac resynchronisation therapy.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04537455
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Left Bundle-Branch Block
Currently open trials in the same condition.
- NCT05760924 — Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders · NA · recruiting
- NCT06488989 — Left Bundle Branch Area Pacing in Patients With Heart Failure · NA · active not recruiting
- NCT05814263 — HIS Alternative II - UK Site · NA · recruiting
- NCT05769036 — Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients · NA · recruiting
- NCT05652218 — REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT) · NA · active not recruiting
Other Imperial College London trials
Trials by the same sponsor.
- NCT06035861 — Endothelial Cell Activation and Total Pulmonary Resistance in PAH · NA · not yet recruiting
- NCT07397455 — Development of a Controlled Human Infection Model for Assessment of SARS-CoV-2 Omicron Subvariants · Phase 1 · not yet recruiting
- NCT07422532 — A Multi-centre Trial to Assess the Efficacy and Safety of the Omnipod 5 System in People With Type 2 Diabetes Undergoing · NA · not yet recruiting
- NCT07389031 — Maralixibat for Intrahepatic Cholestasis of Pregnancy · Phase 2 · not yet recruiting
- NCT07358897 — Gender Affirming Hormone Therapy and Immune Function in Trans Individuals - The GIFT Study · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04537455 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Imperial College London
- Last refreshed: 23 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04537455.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing