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NCT04524130
Intraoperative Lidocaine and Combined With Ketamine on Opioid After Bariatric Surgery
Phase 4 trial testing Lidocaine Hydrochloride in Laparoscopic Bariatric Surgery in 87 participants. Completed in 31 January 2025.
30 October 2024
Quick facts
| Lead sponsor | Mahidol University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 87 |
| Start date | 1 April 2021 |
| Primary completion | 30 October 2024 |
| Estimated completion | 31 January 2025 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Lidocaine Hydrochloride (Lidocaine Hydrochloride) — full drug profile →
- Ketamine (ketamine) — full drug profile →
- Placebo
Conditions studied
- Laparoscopic Bariatric Surgery — all drugs for Laparoscopic Bariatric Surgery →
Sponsor
Mahidol University
Who can join
18 and older, any sex, with Laparoscopic Bariatric Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The most effective long-term treatment for obesity is bariatric surgery, however, postoperative pain control is challenging in these group of population. Opioid-sparing technique with multimodal analgesia is recommended but the evidence supported is still limited. Multimodal analgesia, particularly lidocaine and ketamine, has been used effectively in various type of surgery. However, the evidence supported their use in obese patients undergoing bariatric surgery is limited.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04524130
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Mahidol University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04524130 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mahidol University
- Last refreshed: 9 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04524130.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing