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NCT04518579: tumorimmunity
Epidural-inhalational Versus Epidural-intravenous Anaesthesia on Anti-tumor Immunity in Patients With Cancer Colon
NA trial testing thoracic epidural in Immunity Factors in Cancer Colon Patients in 48 participants. Completed in 1 August 2020.
1 June 2020
Quick facts
| Lead sponsor | South Egypt Cancer Institute |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 48 |
| Start date | 15 April 2018 |
| Primary completion | 1 June 2020 |
| Estimated completion | 1 August 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- thoracic epidural — full drug profile →
Conditions studied
- Immunity Factors in Cancer Colon Patients — all drugs for Immunity Factors in Cancer Colon Patients →
Sponsor
South Egypt Cancer Institute
Who can join
Adults 20 to 70, any sex, with Immunity Factors in Cancer Colon Patients. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Surgery is the primary treatment for colon cancer. However, the rate of recurrence or metastasis in colon cancer can be as high as 30%, even in stages 1 and 2 . Most colon cancer-related deaths are caused by metastatic disease . Many patients with colon cancer harbour micrometastases and disseminated tumour cells at the time of surgery . Whether the micrometastases develop into clinically significant metastases depends on the immune system's ability to eradicate them.The aim of the study is to declare the effect of epidural-intravenous based anesthetic technique on anti-tumor immunity and in comparison to epidural inhalational based anesthetic technique in patients undergoing open surgical resection of colon cancer.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04518579
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of thoracic epidural
Trials testing the same drug.
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- NCT03933592 — Ultrasound Guided Serratus Plane Block Versus Thoracic Epidural for Post Thoracotomy Pain · NA · completed
- NCT03719248 — Thoracic Epidural Reduces Risks of Increased Left Ventricular Mass Index During Coronary Artery Bypass Graft Surgery · NA · completed
Other South Egypt Cancer Institute trials
Trials by the same sponsor.
- NCT07438366 — Adding Magnesium Sulphate to Combined Pectointercostal Plane and Erector Spinae Plane Blocks for Acute and Chronic Post- · NA · not yet recruiting
- NCT07434232 — Adding Magnesium Sulfate to Combined Pecto-Intercostal & Serratus Anterior Planes Block on Post-operative Analgesia in P · NA · not yet recruiting
- NCT07434206 — Safety and Efficacy of Dexmedetomidine in Controlling Hemodynamics During Resection of Active Thyroid Secreting Tumors · Phase 2, PHASE3 · active not recruiting
- NCT05279378 — Correlation of Lung Ultrasonography With Chest CT Findings in Cancer Patients With COVID-19 Viral Pneumonia · completed
- NCT05587608 — US-guided Thoracic Spinal Epidural Anesthesia VS GA for Abdominal and Breast Surgeries · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04518579 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by South Egypt Cancer Institute
- Last refreshed: 21 August 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04518579.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing