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NCT04499898
Carvedilol Versus Endoscopic Band Ligation for Primary Prophylaxis of Oesophageal Variceal Bleeding
Phase 2, PHASE3 trial testing Carvedilol in Esophageal Varices in 306 participants. Currently enrolling.
1 December 2030
Quick facts
| Lead sponsor | Sherief Abd-Elsalam |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 306 |
| Start date | 1 October 2018 |
| Primary completion | 1 December 2030 |
| Estimated completion | 10 December 2030 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Carvedilol (CARVEDILOL) — full drug profile →
- Endoscopic band ligation
Conditions studied
- Esophageal Varices — all drugs for Esophageal Varices →
Sponsor
Sherief Abd-Elsalam — full company profile →
Who can join
18 and older, any sex, with Esophageal Varices. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Carvedilol versus endoscopic band ligation for primary prophylaxis of oesophageal variceal bleeding in cirrhotic patients with arterial hypertension
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04499898
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Carvedilol
Trials testing the same drug.
- NCT07322237 — DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis · Phase 4 · recruiting
- NCT07521332 — Apixaban-PK Trial: Preventing Portal Hypertension Complications in Cirrhosis · Phase 4 · recruiting
- NCT07465471 — Carvedilol and Midodrine Versus Carvedilol Alone in Preventing Early Rebleed in Patients With Cirrhosis. · NA · not yet recruiting
- NCT07352228 — Carvedilol vs. Propranolol for Preventing Rebleeding After Endoscopic Treatment of Cirrhotic Varices · Phase 4 · enrolling by invitation
- NCT06964464 — Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardio · Phase 4 · recruiting
Other recruiting trials for Esophageal Varices
Currently open trials in the same condition.
- NCT07122622 — 2D-shear Wave Spleen Elastography in Clinically Significant Portal Hypertension and High-risk Varices · recruiting
- NCT06881082 — Cross-section Band Ligation Versus Stepladder Band Ligation of Esophageal Varices · NA · recruiting
- NCT05979935 — A Digital Tongue Diagnosis Model for High- and Low-risk Esophagogastroduodenal Varices in Cirrhosis · active not recruiting
Other Sherief Abd-Elsalam trials
Trials by the same sponsor.
- NCT05291455 — Lacosamide in Neonatal Status Epilepticus · Phase 3 · unknown
- NCT04766177 — Role of Bumetanide in Treatment of Autism · Phase 3 · recruiting
- NCT04499885 — Potential Role of Gastric Lavage by Paraffin Oil in Acute Aluminum Phosphide Poisoning · NA · recruiting
- NCT04499755 — Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics · Phase 3 · recruiting
- NCT04216199 — Role of Point of Care Ultrasound in Endotracheal Tube Placement · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04499898 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sherief Abd-Elsalam
- Last refreshed: 5 August 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04499898.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing