Sherief Abd-Elsalam
Quick facts
Marketed products
- Coenzyme Q
- FOLFERI · Other
- Folferi and celecoxib · Oncology
FOLFIRI chemotherapy combined with celecoxib inhibits tumor cell division through fluorouracil and irinotecan while reducing inflammation via COX-2 inhibition. - Quadruple therapy · Virology/Hepatology
Quadruple therapy combines four antiviral agents to simultaneously target multiple stages of viral replication and host factors. - Sofosbuvir and Ledipasvir or sofosbuvir and daklatasuvir
Phase 3 pipeline
- cardio-selective beta blocker group · Cardiovascular
Blocks beta-1 adrenergic receptors to reduce heart rate and blood pressure. - CHOP Plus Famotidine · Oncology
CHOP Plus Famotidine combines cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP chemotherapy) with famotidine, a histamine H2-receptor antagonist, to enhance chemotherapy efficacy and reduce gastric toxicity. - CHOP Plus Lanzoprazole · Oncology; Gastroenterology
CHOP Plus Lansoprazole combines chemotherapy (cyclophosphamide, doxorubicin, vincristine, prednisone) with a proton pump inhibitor to treat Helicobacter pylori infection and gastric conditions. - Classic treatment · Oncology
This drug works by inhibiting the PD-1 receptor, which is involved in the immune system's response to cancer cells. - Doxicycline · Other
- Folfox with avastin · Oncology
FOLFOX chemotherapy combined with bevacizumab (Avastin) kills cancer cells through DNA damage while blocking tumor blood vessel formation. - Metronidazole(MTZ) · Infectious Disease
Metronidazole is a nitroimidazole antibiotic that disrupts bacterial and parasitic DNA by generating reactive oxygen species after being reduced inside microbial cells. - Nigetella salivata
Nigetella salivata's mechanism of action is not well-documented. - nonselective beta blocker · Cardiovascular
Blocks the action of beta-adrenergic receptors, leading to decreased heart rate and blood pressure. - Nucleo CMP Forte · Immunology; Nutritional support
Nucleo CMP Forte is a nucleotide-based supplement designed to support cellular energy metabolism and immune function through provision of cytidine monophosphate and related nucleotide precursors. - Pantoprazole high dose · Gastroenterology
Pantoprazole is a proton pump inhibitor that suppresses gastric acid secretion by irreversibly blocking the H+/K+-ATPase enzyme in gastric parietal cells. - Pantoprazole low dose · Gastroenterology
Pantoprazole is a proton pump inhibitor that suppresses gastric acid secretion by irreversibly blocking the H+/K+-ATPase enzyme in gastric parietal cells. - Sofosbuvir and Daklatasuvir · Infectious Disease
Sofosbuvir and Daklatasuvir work together to inhibit the HCV NS5B RNA-dependent RNA polymerase and NS5A protein, respectively, to treat hepatitis C virus infection.
Competitive intelligence
For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors: