Last reviewed 2026-04-23 · How we verify

nonselective beta blocker

Blocks the action of beta-adrenergic receptors, leading to decreased heart rate and blood pressure.

Blocks the action of beta-adrenergic receptors, leading to decreased heart rate and blood pressure. Used for Hypertension, Angina pectoris.

At a glance

Mechanism of action

Nonselective beta blockers, such as the one in question, work by binding to beta-adrenergic receptors in the heart and blood vessels, thereby reducing the effects of the sympathetic nervous system. This results in decreased heart rate, reduced cardiac output, and vasodilation, ultimately leading to decreased blood pressure and reduced myocardial oxygen demand.

Approved indications

• Hypertension
• Angina pectoris

Common side effects

• Bradycardia
• Hypotension
• Dyspnea

Key clinical trials

• LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB (NA)
• Endoscopic Variceal Ligation vs Carvedilol for the Prevention of First Esophageal Variceal Bleeding in Patients With HCC (PHASE4)
• Carvedilol Plus EVL or Not for the Primary Prevention of Esophageal Variceal Bleeding in Carvedilol Non-responders (PHASE4)
• To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites (PHASE3)
• Carvedilol vs. Propranolol in Second Prophylaxis of Variceal Bleeding (NA)
• Effects of Beta-blockade on Platelet Aggregation in Acute Coronary Syndrome (PHASE4)
• The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma (PHASE4)
• Clinical Study Evaluating Beta Blockers Use and Fracture Risk in Patients With Primary Osteoporosis (PHASE3)

Primary sources

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