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NCT04489355
The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy
trial testing coronary artery bypass graft (CABG) with surgical ventricular restoration (SVR) and mitral repair (MR) in Cardiovascular Diseases in 260 participants. Completed in 1 May 2024.
28 January 2023
Quick facts
| Lead sponsor | Tomsk National Research Medical Center of the Russian Academy of Sciences |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 260 |
| Start date | 28 January 2013 |
| Primary completion | 28 January 2023 |
| Estimated completion | 1 May 2024 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- coronary artery bypass graft (CABG) with surgical ventricular restoration (SVR) and mitral repair (MR)
Conditions studied
- Cardiovascular Diseases — all drugs for Cardiovascular Diseases →
- Chronic Heart Failure — all drugs for Chronic Heart Failure →
- Ischemic Cardiomyopathy — all drugs for Ischemic Cardiomyopathy →
Sponsor
Tomsk National Research Medical Center of the Russian Academy of Sciences
Who can join
Adults 18 to 70, any sex, with Cardiovascular Diseases or Chronic Heart Failure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study focuses on the development of a new personalized approach to diagnostics and surgical treatment of patients with ischemic cardiomyopathy. The algorithm for selection of patients for certain type of cardiac surgery will be developed. The models for prediction of the risks and outcomes of cardiac surgery will be elaborated to reduce the rate of complications in the early and long-term postoperative period in patients with ischemic cardiomyopathy. Imaging modalities, methods for assessement of structural and functional state of the myocardium, biochemistry testing, immunohistochemical examination, and myocardial biopsy studies will be used to achieve these goals.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04489355
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04489355 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tomsk National Research Medical Center of the Russian Academy of Sciences
- Last refreshed: 21 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04489355.
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