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NCT07018895
Personalized Hypoxic-hyperoxic Preconditioning in Elderly People
NA trial testing Sham treatment in Preconditioning in 20 participants. Completed in 3 October 2025.
1 September 2025
Quick facts
| Lead sponsor | Tomsk National Research Medical Center of the Russian Academy of Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 20 |
| Start date | 1 July 2025 |
| Primary completion | 1 September 2025 |
| Estimated completion | 3 October 2025 |
| Sites | 1 location across Russia |
Drugs / interventions tested
- Sham treatment — full drug profile →
- FiO2 reduced by 20% alternating with 34% FiO2 — full drug profile →
Conditions studied
- Preconditioning — all drugs for Preconditioning →
Sponsor
Tomsk National Research Medical Center of the Russian Academy of Sciences
Who can join
Adults 60 to 74, any sex, with Preconditioning. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates an original protocol of personalized hypoxic-hyperoxic preconditioning utilizing a personalized approach on the basis of cerebral tissue oxygenation assessed with near-infrared spectroscopy. 20 healthy elderly volunteers will be randomized into two equal groups. Subjects of the experimental group will undergo personalized sessions of intermittent hypoxic-hyperoxic training (IHHT) based on the cerebral tissue oximetry index assessed with near-infrared spectroscopy with a target reduction of 20%. Subjects of the control group (sham treatment) will undergo placebo procedures with atmospheric air.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07018895
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07018895 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tomsk National Research Medical Center of the Russian Academy of Sciences
- Last refreshed: 9 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07018895.
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