NCT04487535 is a NA clinical trial of Cytokine level in Total Knee Arthroplasty, sponsored by Hacettepe University.

Who is sponsoring NCT04487535?

NCT04487535 is sponsored by Hacettepe University.

What drugs are being tested in NCT04487535?

Interventions in NCT04487535: Cytokine level.

What condition does NCT04487535 study?

NCT04487535 studies Total Knee Arthroplasty.

Is NCT04487535 still recruiting?

NCT04487535 is currently completed. Last updated 27 July 2020.

Last reviewed 2020-07-27 · How we verify

NCT04487535

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Relationship Between Preoperative Serum Cytokine Level and Lenght of Stay in Hospital, Postoperative Pain Intensity, Functional Status, Joint Position Sense and X Ray Findings

Completed NA Last updated 27 July 2020

What this trial tests

NA trial testing Cytokine level in Total Knee Arthroplasty in 29 participants. Completed in 1 February 2020.

Timeline

1 December 2018

Primary endpoint
1 January 2020

1 February 2020

Quick facts

Lead sponsor	Hacettepe University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	29
Start date	1 December 2018
Primary completion	1 January 2020
Estimated completion	1 February 2020
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Cytokine level

Conditions studied

Total Knee Arthroplasty — all drugs for Total Knee Arthroplasty →

Sponsor

Hacettepe University

Who can join

Adults 45 to 75, any sex, with Total Knee Arthroplasty. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Serum cytokines was assosiated with symptoms and progression of osteoartritis. It is unknown whether these cytokines have a predictive role on severity of symptoms after total knee arthroplasty (TKA) or not. The aim of this study is to investigate the relationships between the preoperative serum cytokine level (SCL) and lenght of stay in hospital, postoperative pain intensity, functional status, joint position sense and X ray. Grade 4 osteoartritis degeneration who intern the hospital for total knee arthroplasty surgery. Serum Cytokine Levels (IL-6, TNFα, IL-1β) will be assessed before surgery. Pain intensity at rest/activity and valgite angle will be evaluated before surgery, postoperative 72 hour and postoperative 6 weeks. Functional status and joint position sense will be assessed before surgery and 6 weeks after surgery. Lenght of stay in hospital (LOS) will be recorded.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Total Knee Arthroplasty

Currently open trials in the same condition.

NCT07524387 — Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty · NA · recruiting
NCT07511842 — REST-Knee: A Pilot RCT of 72-Hour Knee Immobilization and Pain Outcomes · NA · recruiting
NCT07324954 — Methylene Blue in Total Knee Arthroplasty (TKA) · Phase 1 · recruiting
NCT07336160 — ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty · NA · recruiting
NCT07371390 — Minimal Sedation During Knee Replacement Surgery · NA · recruiting

Other Hacettepe University trials

Trials by the same sponsor.

NCT07522060 — Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Us · not yet recruiting
NCT07390162 — The Effect of Changes in the Frequency of Endotracheal Tube Repositioning in Intensive Care Units on the Prevention of O · NA · not yet recruiting
NCT07579676 — DEVELOPMENT AND PSYCHOMETRIC EVALUATION OF THE NEUROCOGNITIVE UPPER EXTREMITY TESTS: A RELIABILITY AND VALIDITY STUDY · not yet recruiting
NCT07524842 — Clinical Performance of Three Different Restorative Materials · NA · not yet recruiting
NCT07439861 — The Effect of Cognitive Dual-Task on Athletic Performance Parameters in Volleyball Players With and Without Chronic Ankl · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04487535 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hacettepe University
Last refreshed: 27 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04487535.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing