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NCT04472442
Intermittent Hypoxia Paired with High Intensity Training in Brain Injury
NA trial testing Intermittent hypoxia in Brain Injuries in 35 participants. Completed in 30 June 2023.
30 June 2023
Quick facts
| Lead sponsor | Indiana University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 35 |
| Start date | 1 August 2020 |
| Primary completion | 30 June 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Intermittent hypoxia
- Sham hypoxia
Conditions studied
- Brain Injuries — all drugs for Brain Injuries →
Sponsor
Indiana University
Who can join
Adults 18 to 85, any sex, with Brain Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The central hypotheses are that HIT combined with AIH results in: 1) greater locomotor gains as compared to HIT alone; 2) improvements in gait quality and motor coordination during walking, and 3) changes in measures of community participation and integration.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Acute Intermittent Hypoxia With High-Intensity Gait Training in Chronic Stroke: A Phase II Randomized Crossover Trial.
Hornby TG, Plawecki A, Lotter JK, Shoger LH, et al · · 2024 · cited 8× · PMID 38860389 · DOI 10.1161/strokeaha.124.047261
Verify or expand the search:
- PubMed search for NCT04472442
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT05423470 — Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals · NA · completed
- NCT05898685 — Effect of a Single Session of Intermittent Hypoxia on Hematological Variables · NA · completed
Other recruiting trials for Brain Injuries
Currently open trials in the same condition.
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- NCT06511804 — Correlation Between Noninvasive Blood Vessel Functionality Parameters and Cerebral Hemodynamics in Neurocritical Care Pa · recruiting
- NCT06863025 — Effects of Neurofeedback Training on Attentional Deficits in Patients With Acquired Brain Injury · NA · active not recruiting
- NCT06571032 — Electroencephalography in the Management of Neuroelectric Stimulation in Patients With Severe Traumatic Brain Injuries · recruiting
Other Indiana University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04472442 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Indiana University
- Last refreshed: 17 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04472442.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing