NCT04471571

A Comparison of the Effectiveness of Resin Infiltration Treatment Versus a Combined Treatment of Microabrasion and Resin Infiltration for the Management of Affected Incisors in Molar Incisor Hypomineralization (MIH) Cases

Status unknown NA Last updated 14 July 2020

What this trial tests

NA trial testing Resin infiltration and microabrasion for MIH-affected incisors in Molar Incisor Hypomineralization in 30 participants. Status unknown.

Timeline

1 January 2021

Primary endpoint
1 January 2022

1 June 2022

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	30
Start date	1 January 2021
Primary completion	1 January 2022
Estimated completion	1 June 2022

Drugs / interventions tested

• Resin infiltration and microabrasion for MIH-affected incisors
• Resin infiltration for MIH-affected incisors

Conditions studied

• Molar Incisor Hypomineralization — all drugs for Molar Incisor Hypomineralization →

Sponsor

Cairo University

Who can join

Adults 7 to 16, any sex, with Molar Incisor Hypomineralization. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

• Change in the aesthetics and amount of color masking of the lesion
  Time frame: 12 months
  Vita Easyshade Advance® spectrophotometer (Vita Zahnfabrik, Sackingen, Germany) will be used to evaluate the change in color of the teeth selected in the study before and after the treatment. L\*, a\*, and b\* values will be recorded for each tooth based on the CIEL\*a\* b\* color space. The value of color differences or color masking (∆E) will be clinically evaluated by the formula ∆E=\[(∆L\*)2+(

Sponsor's own description

The prevalence of molar incisor hypomineralization is relatively high. It has been reported that MIH-affected children experience a wide range of negative impacts because of having visible enamel opacities on their incisors whether these teeth show post eruptive breakdown or not. The management of MIH is challenging with a broad spectrum of treatment modalities being available. However, there are no clear guidelines available to aid in clinical decision making. Possible treatment options for anterior teeth with MIH include: Microabrasion, resin infiltration, tooth bleaching, etch-bleach and seal technique and composite restorations or veneers. It is believed that these methods could be used alone or in a combination of methods to achieve better aesthetic results.

For MIH affected-incisors microabrasion and resin infiltration are acceptable treatment options which could be used alone or in a combination. Accordingly, the aim of this study is to compare the clinical outcomes of using resin infiltration either alone or combined with microabrasion for the management of MIH affected incisors.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.