NCT04471454 is a clinical trial in Bipolar Depression, sponsored by Shanghai Mental Health Center.

Who is sponsoring NCT04471454?

NCT04471454 is sponsored by Shanghai Mental Health Center.

What condition does NCT04471454 study?

NCT04471454 studies Bipolar Depression.

Is NCT04471454 still recruiting?

NCT04471454 is currently completed. Last updated 26 October 2021.

Last reviewed 2021-10-26 · How we verify

NCT04471454

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Verification of the Reliability and Validity of THINC-it Tool in Bipolar Depression

Completed Last updated 26 October 2021

What this trial tests

trial in Bipolar Depression in 200 participants. Completed in 30 September 2021.

Timeline

5 July 2020

Primary endpoint
30 September 2021

30 September 2021

Quick facts

Lead sponsor	Shanghai Mental Health Center
Status	Completed
Study type	OBSERVATIONAL
Enrollment	200
Start date	5 July 2020
Primary completion	30 September 2021
Estimated completion	30 September 2021
Sites	1 location across China

Conditions studied

Bipolar Depression — all drugs for Bipolar Depression →

Sponsor

Shanghai Mental Health Center — full company profile →

Who can join

Adults 18 to 65, any sex, with Bipolar Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is some cognitive impairment in patients with bipolar depression. THINC-it is a simple, fast and free cognitive assessment tool. It has good reliability and validity in patients with depression, but its application in patients with bipolar depression is not clear. The purpose of this study is to verify the reliability and validity of THINC-it cognitive test in bipolar depression, and to further explore the difference of cognitive impairment between attack and remission of bipolar depression, so as to provide empirical research basis for clinical evaluation-based treatment.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Validation of the THINC-It Tool for Assessment of Cognitive Impairment in Patients with Bipolar Depression.
Zhu N, Zhang W, Huang J, Su Y, et al · · 2023 · cited 4× · PMID 36874958 · DOI 10.2147/ndt.s401095
The THINC-it tool: temporal sensitivity to change over time.
Zhu N, Huang J, Su Y, Lu J, et al · · 2024 · PMID 39472833 · DOI 10.1186/s12888-024-06170-8

Verify or expand the search:

Other recruiting trials for Bipolar Depression

Currently open trials in the same condition.

NCT07266545 — RNA Editing as a Biomarker of Antidepressant Response in Unipolar and Bipolar Depression (EDIT-ANDRE) · Phase 4 · recruiting
NCT07246044 — HD-tDCS for Adolescent Bipolar Depression Targeting S1 · NA · recruiting
NCT07121894 — Ketogenic Intervention for Bipolar Depression · NA · recruiting
NCT07108257 — Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for the Treatment of Refractory Bipolar Depression · NA · recruiting
NCT05603104 — Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First- · Phase 3 · recruiting

Other Shanghai Mental Health Center trials

Trials by the same sponsor.

NCT07480408 — Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD · NA · not yet recruiting
NCT07479771 — tTIS Targeted of the Striatum as an Intervention for MUD Patients · NA · not yet recruiting
NCT07472673 — Transcranial Temporal Interference Stimulation Targeted of the Amygdala as an Intervention for Alcohol Use Disorder Pati · NA · not yet recruiting
NCT07484750 — Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD · NA · recruiting
NCT07311655 — Validation of the Accuracy of an AI-Based System for Diagnosing Anxiety Disorders · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04471454 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Shanghai Mental Health Center
Last refreshed: 26 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04471454.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing