Last reviewed · How we verify
NCT04449068: POSTSTIC
Observational Database on Deep Brain Stimulation in Tourette Syndrome
trial testing Neurological and neuropsychological Follow-up after deep brain stimulation in Tourette Syndrome in 20 participants. Currently enrolling.
12 June 2036
Quick facts
| Lead sponsor | Assistance Publique - Hôpitaux de Paris |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 12 January 2021 |
| Primary completion | 12 June 2036 |
| Estimated completion | 12 June 2036 |
| Sites | 1 location across France |
Drugs / interventions tested
- Neurological and neuropsychological Follow-up after deep brain stimulation
- EEG recordings
Conditions studied
- Tourette Syndrome — all drugs for Tourette Syndrome →
Sponsor
Assistance Publique - Hôpitaux de Paris — full company profile →
Who can join
15 and older, any sex, with Tourette Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Within an ongoing deep brain stimulation (DBS) program for Tourette syndrome (TS) at the Department of Neurology, Pitié-Salpêtrière Hospital, Paris/France, the investigator team plans to evaluate patients pre-operatively and then at one year intervals post-operatively until the 5-year mark has been achieved. The investigator team will investigate tic severity, psychiatric co-morbidities, quality of life, and neuropsychological measures.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Deep Brain Stimulation for the Management of Refractory Neurological Disorders: A Comprehensive Review.
Rissardo JP, Vora NM, Tariq I, Mujtaba A, et al · · 2023 · cited 17× · PMID 38004040 · DOI 10.3390/medicina59111991
Verify or expand the search:
- PubMed search for NCT04449068
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Tourette Syndrome
Currently open trials in the same condition.
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- NCT06679790 — Trajectories of Change in Tourette Syndrome · NA · recruiting
- NCT06678737 — CBIT+TMS R33 Phase · Phase 2 · recruiting
- NCT06909656 — Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome · NA · recruiting
- NCT06785532 — Effect of RNS in Treatment-refractory Tourette's Syndrome · NA · recruiting
Other Assistance Publique - Hôpitaux de Paris trials
Trials by the same sponsor.
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- NCT07505394 — Efficacy of a Prediction Model-based Algorithm to PREVENT Drug-induced Impulse Control Disorders in Parkinson's Disease · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04449068 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assistance Publique - Hôpitaux de Paris
- Last refreshed: 6 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04449068.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing