Who is sponsoring NCT04447950?

NCT04447950 is sponsored by Assuta Medical Center.

What drugs are being tested in NCT04447950?

Interventions in NCT04447950: Type 2/posterior Quadratus Lumborum block, Placebo block with Saline.

What condition does NCT04447950 study?

NCT04447950 studies Spinal Stenosis Lumbar, Spondylolisthesis, Fusion of Spine, Lumbar Region, Degeneration Spine.

Is NCT04447950 still recruiting?

NCT04447950 is currently status unknown. Last updated 24 June 2020.

Last reviewed 2020-06-24 · How we verify

NCT04447950

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

A Randomized, Double Blind, Placebo Controlled Evaluation Trial of the Benefit in Quadratus Lumborum Block as a Postoperative Analgesic Technique for a Lumbar Spine Decompression and Fusion Surgery

Status unknown NA Last updated 24 June 2020

What this trial tests

NA trial testing Type 2/posterior Quadratus Lumborum block in Spinal Stenosis Lumbar in 100 participants. Status unknown.

Timeline

1 June 2020

Primary endpoint
1 May 2021

1 August 2021

Quick facts

Lead sponsor	Assuta Medical Center
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	100
Start date	1 June 2020
Primary completion	1 May 2021
Estimated completion	1 August 2021
Sites	1 location across Israel

Drugs / interventions tested

Type 2/posterior Quadratus Lumborum block
Placebo block with Saline

Conditions studied

Spinal Stenosis Lumbar — all drugs for Spinal Stenosis Lumbar →
Spondylolisthesis — all drugs for Spondylolisthesis →
Fusion of Spine, Lumbar Region — all drugs for Fusion of Spine, Lumbar Region →
Degeneration Spine — all drugs for Degeneration Spine →

Sponsor

Assuta Medical Center

Who can join

Adults 18 to 80, any sex, with Spinal Stenosis Lumbar or Spondylolisthesis. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Change in the use of post-operative narcotics
Time frame: Will be reported for each postoperative day during the inpatient stay of the patient to a maximum of 7 days.
Difference in MME (morphine milligrams equivalent) of inpatient narcotics consumption.

Sponsor's own description

Lumbar spinal decompression and fusion is a commonly performed procedure fro neural impingement and back pain from a variety of pathologies. The importance of pain control in the postoperative period for spinal surgery has been discussed and proven extensively, with both immediate and delayed reduction in complications and improved clinical results. Quadratus lumborum (QL) block was introduced in 2007 and is performed under ultrasound guidance for perioperative pain management in various surgeries.However, the plane for a posterior QL block can be easily reached during open midline spinal surgery. The investigators hypothesize that the posterior QL block is an effective analgesic tool for lumbar laminectomy surgery, because in lumbar laminectomy the quadratus lumborum is already exposed and is in direct visual contact. For that reason it is imperative to test the benefits of this procedure. This is a double blinded randomized control study to assess the results of intra-operative QL block performed for lumbar decompression and fusion.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Spinal Stenosis Lumbar

Currently open trials in the same condition.

NCT07348523 — Comparison of the Postoperative Analgesic Efficacy of Classical and Modified Erector Spinae Plane Blocks After Lumbar Sp · NA · recruiting
NCT06367855 — Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF · Phase 4 · recruiting
NCT06393959 — Relief of Lumbar Spinal Stenosis Symptoms · NA · recruiting
NCT05253326 — The Effect of Progressive Muscle Relaxation Exercises on Pain and Disability After Spinal Surgery · NA · recruiting

Other Assuta Medical Center trials

Trials by the same sponsor.

NCT06950684 — Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptati · NA · not yet recruiting
NCT05122013 — Remote Intervention for Weight Regain After Sleeve Gastrectomy · NA · completed
NCT04741113 — The Effect of an Education Module to Reduce Weight Bias Among Healthcare Professionals in a Private Hospital Setting · NA · completed
NCT04451499 — The Effect of Adding Smartphone-based Platform to the Bariatric Surgery Preparation Process · NA · completed
NCT05134389 — Survey on GI and Nutritional Parameters Among OAGB Patients From Different Countries · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04447950 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Assuta Medical Center
Last refreshed: 24 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04447950.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing