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NCT06367855: MIS-TLIF
Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF
Phase 4 trial testing Dexamethasone in Spinal Stenosis Lumbar in 60 participants. Currently enrolling.
30 November 2025
Quick facts
| Lead sponsor | Potsawat Surabotsopon |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 May 2024 |
| Primary completion | 30 November 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Thailand |
Drugs / interventions tested
- Dexamethasone (dexamethasone) — full drug profile →
- Normal saline
Conditions studied
- Spinal Stenosis Lumbar — all drugs for Spinal Stenosis Lumbar →
- Disc Degeneration — all drugs for Disc Degeneration →
- Disc Disease — all drugs for Disc Disease →
- Fusion of Spine — all drugs for Fusion of Spine →
Sponsor
Potsawat Surabotsopon
Who can join
Adults 50 to 80, any sex, with Spinal Stenosis Lumbar or Disc Degeneration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and improve patient outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06367855
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dexamethasone
Trials testing the same drug.
- NCT07543458 — Therapeutics for Moderate and Severe Dengue · Phase 3 · not yet recruiting
- NCT07175415 — HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological · Phase 1, PHASE2 · not yet recruiting
- NCT07513129 — A Phase 1 Study Of Venetoclax, Dexamethasone, Bortezomib, And Daratumumab (VDBD) For Adolescent And Young Adult Patients · Phase 1 · not yet recruiting
- NCT07444710 — Testing the Addition of an Anti-Cancer Drug, Glofitamab, to the Usual Chemotherapy Treatment (Alternating R-CHOP/R-DHAP) · Phase 1 · not yet recruiting
- NCT07387926 — Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+ · Phase 1, PHASE2 · not yet recruiting
Other recruiting trials for Spinal Stenosis Lumbar
Currently open trials in the same condition.
- NCT07348523 — Comparison of the Postoperative Analgesic Efficacy of Classical and Modified Erector Spinae Plane Blocks After Lumbar Sp · NA · recruiting
- NCT06393959 — Relief of Lumbar Spinal Stenosis Symptoms · NA · recruiting
- NCT05253326 — The Effect of Progressive Muscle Relaxation Exercises on Pain and Disability After Spinal Surgery · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06367855 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Potsawat Surabotsopon
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06367855.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing