NCT04440969 is a NA clinical trial of Multi-domain intervention in Cognitive Decline, sponsored by Geriatric Education and Research Institute.

Who is sponsoring NCT04440969?

NCT04440969 is sponsored by Geriatric Education and Research Institute.

What drugs are being tested in NCT04440969?

Interventions in NCT04440969: Multi-domain intervention.

What condition does NCT04440969 study?

NCT04440969 studies Cognitive Decline, Cognitive Impairment, Mild.

Is NCT04440969 still recruiting?

NCT04440969 is currently completed. Last updated 22 June 2020.

Last reviewed 2020-06-22 · How we verify

NCT04440969

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of Pilot Community-based Multi-domain Program Older Adults at Risk of Cognitive Impairment

Completed NA Last updated 22 June 2020

What this trial tests

NA trial testing Multi-domain intervention in Cognitive Decline in 199 participants. Completed in 4 March 2020.

Timeline

20 June 2018

Primary endpoint
4 March 2020

4 March 2020

Quick facts

Lead sponsor	Geriatric Education and Research Institute
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	prevention
Enrollment	199
Start date	20 June 2018
Primary completion	4 March 2020
Estimated completion	4 March 2020
Sites	1 location across Singapore

Drugs / interventions tested

Multi-domain intervention

Conditions studied

Cognitive Decline — all drugs for Cognitive Decline →
Cognitive Impairment, Mild — all drugs for Cognitive Impairment, Mild →

Sponsor

Geriatric Education and Research Institute

Who can join

55 and older, any sex, with Cognitive Decline or Cognitive Impairment, Mild. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The multi-domain programme was adapted from a larger international multi-domain interventional study for the Singapore community of older adults at risk of cognitive impairment. This programme comprises nutritional, physical and cognitive components delivered by implementation partners in the community. A dementia risk screening tool developed from the Singapore Longitudinal Ageing Study (SLAS) data was used to screen potential participants. The nutritional component includes nutrition guidance via a nutritional app, while cognition component involves computerised training on a touch screen device and physical aspects involves dual-task exercises.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Implementation and effectiveness of a multi-domain program for older adults at risk of cognitive impairment at neighborhood senior centres.
Ng PEM, Nicholas SO, Wee SL, Yau TY, et al · · 2021 · cited 12× · PMID 33589714 · DOI 10.1038/s41598-021-83408-5
Evaluation of Implementation and Effectiveness of a Pilot Multi-Domain Program for Older Adults at Risk of Cognitive Impairment at Neighborhood Senior Centres – A Randomized Controlled Trial
Ng PEM, Nicholas SO, Wee S, Yau TY, et al · · 2020 · DOI 10.21203/rs.3.rs-44051/v1

Verify or expand the search:

Other trials of Multi-domain intervention

Trials testing the same drug.

NCT05828043 — Brain Aging: Muscle-to-brain Axis Modulates Physio-cognitive Decline · NA · completed
NCT03528005 — Effectiveness of Integrated Care Network · NA · completed

Other recruiting trials for Cognitive Decline

Currently open trials in the same condition.

NCT07220694 — Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairmen · NA · recruiting
NCT07394504 — Effects of Turning Based Dual Task Training on Balance and Mild Cognitive Impairment in Diabetic Peripheral Neuropathy · NA · recruiting
NCT07127965 — Exercise Adherence and Cognitive Decline: Phase 2 · NA · recruiting
NCT07151365 — Plant-based Diets and Healthy Aging · recruiting
NCT07399418 — TRIAD - Tracking Risk in Integrated Alzheimer's Diagnostics. · recruiting

Other Geriatric Education and Research Institute trials

Trials by the same sponsor.

NCT06753643 — An Intrinsic Capacity Identification and Management Programme for Older Adults in Singapore's Primary Care · not yet recruiting
NCT05756478 — Appropriate Prescribing for Older Adults With Multimorbidity (Pro-M) · NA · completed
NCT04788251 — Falls Prevention Evaluation and Development for Older Adults in the Community · NA · completed
NCT04549103 — Effect of Baduanjin on Functional Performance in Pre-Frail/Frail Older Adults · NA · completed
NCT04866316 — Protocol for Multi-site Evaluation of New Community-based Frailty Programme · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04440969 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Geriatric Education and Research Institute
Last refreshed: 22 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04440969.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing