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NCT04437199
Tricaprilin Phase 2 Pilot Study in Migraine
Phase 2 trial testing Tricaprilin in Migraine in 83 participants. Completed in 7 February 2022.
7 February 2022
Quick facts
| Lead sponsor | Cerecin |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 83 |
| Start date | 17 December 2020 |
| Primary completion | 7 February 2022 |
| Estimated completion | 7 February 2022 |
| Sites | 10 locations across Australia |
Drugs / interventions tested
- Tricaprilin — full drug profile →
- Placebo
Conditions studied
- Migraine — all drugs for Migraine →
Sponsor
Cerecin — full company profile →
Who can join
Adults 18 to 70, any sex, with Migraine. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a randomised, double-blind, placebo-controlled, parallel-group, multi-centre study of tricaprilin as AC-SD-03 compared with placebo for the reduction of migraine in participants with frequent migraine.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Tricaprilin (CER-0001) for the preventive treatment of migraine: A phase 2 randomised, double-blind, placebo-controlled pilot study.
Chow L, Presanis J, McIntyre N, Henderson S, et al · · 2024 · cited 1× · PMID 39094432 · DOI 10.1016/j.jns.2024.123147
Verify or expand the search:
- PubMed search for NCT04437199
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Tricaprilin
Trials testing the same drug.
- NCT04187547 — A Phase III Multi Regional Clinical Trial (MRCT) of Tricaprilin in Mild to Moderately Severe Probable Alzheimer's Diseas · Phase 3 · withdrawn
- NCT04727970 — Tricaprilin Infantile Spasms Pilot Study · Phase 1 · completed
- NCT04268953 — Study to Compare the Pharmacokinetics of Daily Administration of Tricaprilin on Ketone Body Production · Phase 1 · completed
- NCT03971123 — Study to Compare the Pharmacokinetics of Tricaprilin Formulations and a Placebo on Ketone Body Production · Phase 1 · completed
- NCT03628352 — Taste-masking Study for Tricaprilin in Sensory Panelists · Phase 1 · completed
Other recruiting trials for Migraine
Currently open trials in the same condition.
- NCT07419607 — MIGRAFIT: Evaluating a Group Therapy Program Combining Physical Activity, Progressive Muscle Relaxation and Psychoeducat · NA · recruiting
- NCT07487701 — Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study · NA · active not recruiting
- NCT07343427 — Impact of GON PRF on Central Sensitization in Migraine Patients · NA · active not recruiting
- NCT07336056 — Nerivio Efficacy Under High-Frequency Use · Phase 4 · active not recruiting
- NCT07385755 — Desvenlafaxine for Preventive Treatment of Frequent Migraines · NA · active not recruiting
Other Cerecin trials
Trials by the same sponsor.
- NCT05628636 — AC-OLE-01-VA Tolerability Study in Healthy Participants Under Different Dosing Conditions · Phase 1 · completed
- NCT05408780 — A Phase 1, Two-part, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Liquid Formulation · Phase 1 · completed
- NCT04187547 — A Phase III Multi Regional Clinical Trial (MRCT) of Tricaprilin in Mild to Moderately Severe Probable Alzheimer's Diseas · Phase 3 · withdrawn
- NCT04727970 — Tricaprilin Infantile Spasms Pilot Study · Phase 1 · completed
- NCT05028114 — Tricaprilin Liquid Formulation PK Study · Phase 1 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04437199 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cerecin
- Last refreshed: 8 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04437199.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing