Who is sponsoring NCT04424160?

NCT04424160 is sponsored by Acibadem University.

What drugs are being tested in NCT04424160?

Interventions in NCT04424160: PRP injection in the endometrium.

What condition does NCT04424160 study?

NCT04424160 studies Asherman Syndrome.

Is NCT04424160 still recruiting?

NCT04424160 is currently completed. Last updated 20 April 2021.

Last reviewed 2021-04-20 · How we verify

NCT04424160

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Platelet Rich Plasma on Endometrium

Completed NA Last updated 20 April 2021

What this trial tests

NA trial testing PRP injection in the endometrium in Asherman Syndrome in 150 participants. Completed in 19 April 2021.

Timeline

15 September 2020

Primary endpoint
19 April 2021

19 April 2021

Quick facts

Lead sponsor	Acibadem University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	150
Start date	15 September 2020
Primary completion	19 April 2021
Estimated completion	19 April 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

PRP injection in the endometrium — full drug profile →

Conditions studied

Asherman Syndrome — all drugs for Asherman Syndrome →

Sponsor

Acibadem University

Who can join

Adults 20 to 45, female only, with Asherman Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period. The endometrial thickness will be assessed under ultrasound and hormone replacement will be started. As the endometrial thickness reaches adequate thickness during ultrasound follow-up, embryo transfer will be performed.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Therapeutic roles of platelet-rich plasma to restore female reproductive and endocrine dysfunction.
Wang X, Li J, Lu W, Gao F, et al · · 2024 · cited 8× · PMID 38654928 · DOI 10.3389/fendo.2024.1374382
A novel technique- subendometrial autologous platelet rich plasma injection in patients with unresponsive thin endometrium undergoing frozen-thawed embryo transfer: a prospective cohort study.
Cakiroglu Y, Tohma YA, Yuceturk A, Karaosmanoglu O, et al · · 2025 · cited 5× · PMID 40098101 · DOI 10.1186/s12884-025-07400-x
A Novel Technique- Subendometrial Autologous Platelet Rich Plasma Injection in Patients with Unresponsive Thin Endometrium Undergoing Frozen-Thawed Embryo Transfer: A prospective cohort study.
Cakiroglu Y, Tohma YA, Yuceturk A, Karaosmanoglu O, et al · · 2024 · DOI 10.21203/rs.3.rs-5290281/v1

Verify or expand the search:

Other recruiting trials for Asherman Syndrome

Currently open trials in the same condition.

NCT04671914 — Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester. · Phase 4 · recruiting

Other Acibadem University trials

Trials by the same sponsor.

NCT07481864 — The Effect of Early-Phase Graded Motor Imagery Following Massive Rotator Cuff Repair. · NA · not yet recruiting
NCT07488377 — Turkish Cognitive Self-Efficacy Questionnaire in Parkinson's Disease · not yet recruiting
NCT07488364 — Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis · not yet recruiting
NCT07488351 — "Self-Compassion and Self-Efficacy in Parkinson's Disease: Associations With Symptoms, Function, and Quality of Life" · not yet recruiting
NCT07413185 — Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and B · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04424160 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Acibadem University
Last refreshed: 20 April 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04424160.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing