Last reviewed · How we verify
NCT04416958: Pace-Conduct
Pacing to Maintain Physiologic Ventricular Activation
trial testing cardiac implantable electronic device (CIED) implantation in Pacemaker DDD in 200 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Klinikum-Fuerth |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 200 |
| Start date | 1 January 2018 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2030 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- cardiac implantable electronic device (CIED) implantation
Conditions studied
- Pacemaker DDD — all drugs for Pacemaker DDD →
- His Bundle Pacing — all drugs for His Bundle Pacing →
- LBB Area Pacing — all drugs for LBB Area Pacing →
- Pacing-Induced Cardiomyopathy — all drugs for Pacing-Induced Cardiomyopathy →
Sponsor
Klinikum-Fuerth
Who can join
18 and older, any sex, with Pacemaker DDD or His Bundle Pacing. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Right ventricular pacing causes ventricular dyssynchrony and may be associated with impaired outcome. In the last decade, several approaches for more physiological pacing became available and were implemented in the latest guidelines. However, compared to conventional device implantation, cardiac resynchronization, His bundle pacing and left bundle area pacing remain demanding procedures in the individual case. Goal of the single center observational "Pace conduct" study is to evaluate implantation success, safety and outcome of pacing methods that maintain physiologic ventricular activation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
His bundle pacing guided by automated intrinsic morphology matching is feasible in patients with narrow QRS complexes.
Bastian D, Gregorio C, Buia V, Walaschek J, et al · · 2022 · cited 1× · PMID 35246595 · DOI 10.1038/s41598-022-07516-6
Verify or expand the search:
- PubMed search for NCT04416958
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Pacemaker DDD
Currently open trials in the same condition.
- NCT06937658 — Remote Alert Pathway To Optimize CaRe of Cardiac Implantable Electrical Devices · NA · recruiting
- NCT06371846 — Comparative Study of the Surface Electrocardiogram Signals During the Implantation of Conduction System Pacing Devices · recruiting
- NCT06318130 — Comparison of Pacing Lead Design on Left Bundle Branch Pacing Outcomes: The LEAD_LBBP Randomized Clinical Trial · NA · active not recruiting
- NCT05015660 — Conduction System Pacing With Left Bundle Branch Pacing as Compared to Standard Right Ventricular Pacing · NA · recruiting
Other Klinikum-Fuerth trials
Trials by the same sponsor.
- NCT04678258 — Zero Fluoroscopy Voltage Guided vs. Linear CTI Ablation · NA · recruiting
- NCT04331249 — Perioperative Management Evaluation in Patients With CIED · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04416958 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Klinikum-Fuerth
- Last refreshed: 15 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04416958.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing