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NCT04416945: COMBAT
Targeting High Risk Populations With Enhanced Reactive Case Detection in Southern Lao Peoples Democratic Republic
NA trial testing Household Reactive Case Detection in Plasmodium Falciparum Malaria in 31,443 participants. Status unknown.
30 September 2021
Quick facts
| Lead sponsor | University of California, San Francisco |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | factorial |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 31,443 |
| Start date | 20 September 2020 |
| Primary completion | 30 September 2021 |
| Estimated completion | 1 November 2021 |
| Sites | 1 location across Laos |
Drugs / interventions tested
- Household Reactive Case Detection
- RACD of cases' co-workers/co-travelers
- Case Management and Follow-up
Conditions studied
- Plasmodium Falciparum Malaria — all drugs for Plasmodium Falciparum Malaria →
- Plasmodium Vivax Malaria — all drugs for Plasmodium Vivax Malaria →
Sponsor
University of California, San Francisco
Who can join
18 Months and older, any sex, with Plasmodium Falciparum Malaria or Plasmodium Vivax Malaria. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study assesses the effectiveness and feasibility of enhanced reactive case detection (RACD) targeting high-risk villages and forest workers for reducing Plasmodium falciparum and Plasmodium vivax transmission in southern Lao Peoples Democratic Republic. The authors hypothesize that enhanced community-based RACD will be more effective than standard of care case management and RACD at reducing P. falciparum and P. vivax confirmed case incidence and parasite prevalence over an 18-month period in Lao Peoples Democratic Republic.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04416945
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04416945 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, San Francisco
- Last refreshed: 16 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04416945.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing