Last reviewed · How we verify
NCT04406467
Retrospective Review of Xen Gel Stent Implantation With Open vs. Closed Conjunctiva Approach
trial testing Xen Gel Stent in Glaucoma, Open-Angle in 137 participants. Completed in 26 August 2020.
26 August 2020
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 137 |
| Start date | 19 November 2017 |
| Primary completion | 26 August 2020 |
| Estimated completion | 26 August 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Xen Gel Stent
Conditions studied
- Glaucoma, Open-Angle — all drugs for Glaucoma, Open-Angle →
Sponsor
Johns Hopkins University
Who can join
Eligibility, any sex, with Glaucoma, Open-Angle. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To measure surgical success of open vs closed conjunctiva with Xen implantation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of Clinical Outcomes with Open Versus Closed Conjunctiva Implantation of the XEN45 Gel Stent.
Do A, McGlumphy E, Shukla A, Dangda S, et al · · 2021 · cited 25× · PMID 33321200 · DOI 10.1016/j.ogla.2020.12.003
Verify or expand the search:
- PubMed search for NCT04406467
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Glaucoma, Open-Angle
Currently open trials in the same condition.
- NCT06964191 — Evaluate Efficacy and Safety of PA5108 Ocular Implants in Primary Open Angle Glaucoma or Ocular Hypertension · Phase 2 · recruiting
- NCT06240312 — Optic Nerve Head Strain as Biomarker for Glaucoma · NA · recruiting
- NCT05405868 — Nicotinamide in Glaucoma (NAMinG): A Randomised, Placebo-controlled, Multi-centre, Phase III Trial · Phase 3 · recruiting
- NCT05710198 — Efficacy of Citicoline Eye Drops 2% on Visual Field Preservation in Patients With Open Angle Glaucoma · Phase 3 · recruiting
- NCT06058598 — Exercise Training in Patients With Glaucoma · NA · active not recruiting
Other Johns Hopkins University trials
Trials by the same sponsor.
- NCT06236542 — Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety · NA · not yet recruiting
- NCT07532252 — Daridorexant for Alcohol Use Disorder · Phase 2 · not yet recruiting
- NCT06687655 — Impact of Exogenous Ketones on Sleep Apnea · Phase 1, PHASE2 · not yet recruiting
- NCT07079111 — 3D Printed Occlusal Splints for Intraoperative Use · NA · not yet recruiting
- NCT02998502 — The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04406467 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 25 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04406467.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing