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NCT04402411
Quadratus Lumborum Block vs Transversus Abdominis Plane Block in Bladder Cancer Surgeries
NA trial testing Quadratus lumborum block in Quadratus Lumborum Block in 63 participants. Status unknown.
30 September 2020
Quick facts
| Lead sponsor | National Cancer Institute, Egypt |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 63 |
| Start date | 1 June 2020 |
| Primary completion | 30 September 2020 |
| Estimated completion | 5 October 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Quadratus lumborum block — full drug profile →
- Transversus abdominis plane block — full drug profile →
- Intravenous opioid — full drug profile →
Conditions studied
- Quadratus Lumborum Block — all drugs for Quadratus Lumborum Block →
- Transversus Abdominis Plane Block — all drugs for Transversus Abdominis Plane Block →
- Bladder Cancer — all drugs for Bladder Cancer →
- Postoperative Pain — all drugs for Postoperative Pain →
Sponsor
National Cancer Institute, Egypt
Who can join
Adults 20 to 80, any sex, with Quadratus Lumborum Block or Transversus Abdominis Plane Block. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Transversus abdominis plane (TAP) block can be used to provide effective analgesia during the postoperative period following a range of surgeries. TAP block administers local anesthetics between the T6 to L1 spinal nerve roots to stop the nerve signal and to alleviate pain for abdominal procedures 4, 5. The viscera are innervated by the vagal nerve (parasympathetic innervation) and by the splanchnic nerves (sympathetic innervation). The splanchnic nerves carry both visceral efferent and afferent nerve fibers. The sensory (or afferent) part of the splanchnic nerves reach the spinal column at certain spinal segments, It is possible to block central visceral pain conduction with thoracic paravertebral blockade or maybe even with the novel quadratus lumborum (QL) block. The effect of the QL block is believed to result from a spread of LA from its lumbar deposition cranially into the thoracic paravertebral space (TPVS), since Carney et al found traces of contrast agent in the TPVS following application of this block. Hence, the QL block would seem to be able to alleviate both somatic and visceral pain.10 The aim of this study is to compare between quadratus lumborum block, transversus abdominis plane block regarding perioperative analgesia after bladder cancer surgeries by measuring intraoperative hemodynamics, postoperative pain scores and morphine consumption in the first 24 h postoperative.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04402411
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Related trials
Other trials of Quadratus lumborum block
Trials testing the same drug.
- NCT07082387 — External Oblique and Rectus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patient · NA · recruiting
- NCT06917807 — Pain Relief Comparison: Pericapsular Nerve Group Versus Quadratus Lumborum Block for Positioning in Femur Fracture Surge · NA · completed
- NCT06588777 — Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumboru · NA · recruiting
- NCT07448987 — Ultrasound Guided Quadratus Lumborum Block, Thoracolumbar Interfascial Plane Block, and Local Anesthetic Infiltration fo · NA · completed
- NCT06420336 — QL vs LAI for Palatoplasty · NA · recruiting
Other recruiting trials for Quadratus Lumborum Block
Currently open trials in the same condition.
- NCT07082387 — External Oblique and Rectus Abdominis Plane Block Versus Quadratus Lumborum Block for Postoperative Analgesia in Patient · NA · recruiting
- NCT06588777 — Ultrasound Guided Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA) Versus Quadratus Lumboru · NA · recruiting
- NCT05089994 — Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy · NA · recruiting
Other National Cancer Institute, Egypt trials
Trials by the same sponsor.
- NCT07424638 — Interscalene Block Versus Anterior Suprascapular Block for Post-Thoracotomy Shoulder Pain · NA · recruiting
- NCT07367568 — Costotransverse Foramen Block With Erector Spinae Plane Block in Modified Radical Mastectomy · NA · recruiting
- NCT07367581 — Costotransverse Foramen Block Versus Thoracic Paravertebral Block in Thoracotomy for Lung Cancer · NA · recruiting
- NCT07337330 — Ultrasound Guided External Oblique Intercostal Plane Block Versus Erector Spinae Block for Post Hepatectomy Pain · NA · not yet recruiting
- NCT07390448 — Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04402411 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Cancer Institute, Egypt
- Last refreshed: 19 October 2020
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