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Transversus abdominis plane block
A regional anesthesia technique that blocks nerve conduction in the transversus abdominis plane to provide anesthesia and analgesia to the abdominal wall.
A regional anesthesia technique that blocks nerve conduction in the transversus abdominis plane to provide anesthesia and analgesia to the abdominal wall. Used for Anesthesia and analgesia for abdominal surgery, Postoperative pain management following abdominal procedures.
At a glance
| Generic name | Transversus abdominis plane block |
|---|---|
| Also known as | Marcaine plain+morphine |
| Sponsor | Diskapi Yildirim Beyazit Education and Research Hospital |
| Drug class | Regional anesthetic technique / Local anesthetic nerve block |
| Modality | Small molecule |
| Therapeutic area | Anesthesia / Pain Management |
| Phase | FDA-approved |
Mechanism of action
The transversus abdominis plane (TAP) block is a peripheral nerve block that delivers local anesthetic to the plane between the internal oblique and transversus abdominis muscles, where the thoracolumbar nerves run. This blocks sensory innervation to the abdominal wall, providing anesthesia during surgery and postoperative pain relief. It is administered via ultrasound-guided injection and is commonly used as part of multimodal anesthesia for abdominal procedures.
Approved indications
- Anesthesia and analgesia for abdominal surgery
- Postoperative pain management following abdominal procedures
Common side effects
- Local anesthetic toxicity
- Bowel or organ perforation
- Hematoma or bleeding
- Infection at injection site
Key clinical trials
- External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative Pain in Laparoscopic Radical Gastrectomy (NA)
- Comparison Between Tranversus Abdominis Plane (TAP) Block With Only Bupivacaine and TAP Block With Bupivacaine Plus Ketamine in Reducing Postoperative Pain After Total Abdominal Hystrectomy (PHASE1, PHASE2)
- Effects of TAP and QLB-1 Blocks on Opioid Consumption (NA)
- Analgesic Comparison of Transversus Fascial Plane and Quadratus Lumborum Blocks in Pediatric Urogenital Procedures (NA)
- Retrolaminar Block Versus Subcostal Transversus Abdominis Plane Block in Liver Resection Surgery (NA)
- EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery (NA)
- Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery (NA)
- The Efficacy and Safety of Liposomal Bupivacaine for Transversus Abdominis Plane Block in Relieving Postoperative Pain After Laparoscopic Surgery (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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