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NCT04399278: EXPIRE
End-eXpiratory Occlusion Test to Predict fluId REsponsiveness in the Operating Room (EXPIRE)
NA trial testing Diagnostic Test: end-expiratory occlusion (EEO) test in Hemodynamic Instability in 40 participants. Completed in 24 March 2021.
24 March 2021
Quick facts
| Lead sponsor | University Hospital, Clermont-Ferrand |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | diagnostic |
| Enrollment | 40 |
| Start date | 3 August 2020 |
| Primary completion | 24 March 2021 |
| Estimated completion | 24 March 2021 |
| Sites | 1 location across France |
Drugs / interventions tested
- Diagnostic Test: end-expiratory occlusion (EEO) test
Conditions studied
- Hemodynamic Instability — all drugs for Hemodynamic Instability →
- General Anesthesia — all drugs for General Anesthesia →
- Surgery — all drugs for Surgery →
- Protective Mechanical Ventilation — all drugs for Protective Mechanical Ventilation →
Sponsor
University Hospital, Clermont-Ferrand
Who can join
18 and older, any sex, with Hemodynamic Instability or General Anesthesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to evaluate the influence of different durations of the end-expiratory occlusion test to predict fluid responsiveness in mechanically ventilated patients in the operating room.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04399278
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Hemodynamic Instability
Currently open trials in the same condition.
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Other University Hospital, Clermont-Ferrand trials
Trials by the same sponsor.
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- NCT07439146 — Risk of Pneumonia in Intubated Patients in Emergency Situations · not yet recruiting
- NCT07427537 — Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients · NA · recruiting
- NCT07330856 — Evaluation of Treatments for Dry or Productive Cough · Phase 4 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04399278 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Clermont-Ferrand
- Last refreshed: 25 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04399278.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing