NCT04396418: STEEER-AF

Stroke Prevention and Rhythm Control Therapy STEEER-AF

Active, enrolled NA Last updated 20 June 2024

What this trial tests

NA trial testing Education in Atrial Fibrillation in 1,732 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

29 December 2021

Primary endpoint
10 January 2024

30 December 2025

Quick facts

Lead sponsor	European Society of Cardiology
Phase	NA
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	other
Enrollment	1,732
Start date	29 December 2021
Primary completion	10 January 2024
Estimated completion	30 December 2025
Sites	70 locations across France, Italy, United Kingdom, Germany, Poland, Spain

Drugs / interventions tested

• Education

Conditions studied

• Atrial Fibrillation — all drugs for Atrial Fibrillation →

Sponsor

European Society of Cardiology

Who can join

18 and older, any sex, with Atrial Fibrillation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A prospective trial with hospitals/health centres across 6 different European countries, being randomised to either a structured education programme as the intervention or no additional education as the control. To determine whether a comprehensive educational programme for healthcare professionals will increase the rate of appropriate stroke prevention and rhythm control therapy in patients with atrial fibrillation (AF) and adherence to Guidelines.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference.
   Schnabel RB, Marinelli EA, Arbelo E, Boriani G, et al · · 2023 · cited 131× · PMID 35894842 · DOI 10.1093/europace/euac062
2. Redefining β-blocker response in heart failure patients with sinus rhythm and atrial fibrillation: a machine learning cluster analysis.
   Karwath A, Bunting KV, Gill SK, Tica O, et al · · 2021 · cited 71× · PMID 34474011 · DOI 10.1016/s0140-6736(21)01638-x
3. Artificial intelligence to enhance clinical value across the spectrum of cardiovascular healthcare.
   Gill SK, Karwath A, Uh HW, Cardoso VR, et al · · 2023 · cited 43× · PMID 36629285 · DOI 10.1093/eurheartj/ehac758
4. Smartphone detection of atrial fibrillation using photoplethysmography: a systematic review and meta-analysis.
   Gill S, Bunting KV, Sartini C, Cardoso VR, et al · · 2022 · cited 37× · PMID 35277454 · DOI 10.1136/heartjnl-2021-320417
5. CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research.
   Kotecha D, Asselbergs FW, Achenbach S, Anker SD, et al · · 2022 · cited 31× · PMID 36562446 · DOI 10.1136/bmj-2021-069048
6. Systematic approach to outcome assessment from coded electronic healthcare records in the DaRe2THINK NHS-embedded randomized trial.
   Wang X, Mobley AR, Tica O, Okoth K, et al · · 2022 · cited 25× · PMID 36712153 · DOI 10.1093/ehjdh/ztac046
7. Improving the diagnosis of heart failure in patients with atrial fibrillation.
   Bunting KV, Gill SK, Sitch A, Mehta S, et al · · 2021 · cited 24× · PMID 33692093 · DOI 10.1136/heartjnl-2020-318557
8. CODE-EHR best practice framework for the use of structured electronic healthcare records in clinical research.
   Kotecha D, Asselbergs FW, Achenbach S, Anker SD, et al · · 2022 · cited 20× · PMID 36208161 · DOI 10.1093/eurheartj/ehac426