Who is sponsoring NCT04394923?

NCT04394923 is sponsored by Centro Medico Teknon.

What drugs are being tested in NCT04394923?

Interventions in NCT04394923: Modification of the pulmonary vein ablation line, Regular PVI ablation.

What condition does NCT04394923 study?

NCT04394923 studies Atrial Arrhythmia.

Is NCT04394923 still recruiting?

NCT04394923 is currently completed. Last updated 19 January 2022.

Last reviewed 2022-01-19 · How we verify

NCT04394923: AWESOME-AF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Relationship Between the Posterior Atrial Wall and the Esophagus: Esophageal Position and Temperature MEasurement During Atrial Fibrillation Ablation.

Completed NA Last updated 19 January 2022

What this trial tests

NA trial testing Modification of the pulmonary vein ablation line in Atrial Arrhythmia in 64 participants. Completed in 15 January 2022.

Timeline

22 June 2020

Primary endpoint
15 March 2021

15 January 2022

Quick facts

Lead sponsor	Centro Medico Teknon
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	64
Start date	22 June 2020
Primary completion	15 March 2021
Estimated completion	15 January 2022
Sites	1 location across Spain

Drugs / interventions tested

Modification of the pulmonary vein ablation line
Regular PVI ablation

Conditions studied

Atrial Arrhythmia — all drugs for Atrial Arrhythmia →

Sponsor

Centro Medico Teknon — full company profile →

Who can join

18 and older, any sex, with Atrial Arrhythmia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A multimodal strategy integrating esophageal visualization with the multidetector computed tomography (MDCT) and simultaneous temperature monitoring has never been put into practice. We have developed an isodistance map (esophageal print) to depict the atrio-esophageal relationship and to analyze the esophageal position peri procedurally. The present randomized study intends to analyze the usefulness of the esophageal print in predicting local thermal heating of the esophagus.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Relationship between the posterior atrial wall and the esophagus: esophageal position and temperature measurement during atrial fibrillation ablation (AWESOME-AF). A randomized controlled trial.
Teres C, Soto-Iglesias D, Penela D, Falasconi G, et al · · 2022 · cited 15× · PMID 35861901 · DOI 10.1007/s10840-022-01302-0
Relationship between the posterior atrial wall and the esophagus: Esophageal position during atrial fibrillation ablation.
Teres C, Soto-Iglesias D, Penela D, Jáuregui B, et al · · 2022 · cited 1× · PMID 35734293 · DOI 10.1016/j.hroo.2022.02.007

Verify or expand the search:

Other recruiting trials for Atrial Arrhythmia

Currently open trials in the same condition.

NCT07271238 — Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures · NA · recruiting
NCT07428967 — AV Node Ablation and CONDUCTion System Pacing for Atrial Fibrillation With Preserved Left Ventricular Function · NA · recruiting
NCT07210151 — Anatomical Navigation for Guided Electrophysiology in AFL and AFib · NA · recruiting
NCT06676072 — A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF: · NA · active not recruiting
NCT06083012 — Clinical and Healthcare Economic OutcoMes From ReAl-worlD Use in Europe of an AI Software During AF Ablation · active not recruiting

Other Centro Medico Teknon trials

Trials by the same sponsor.

NCT07159685 — Sex-Based Differences of LA: Impact on AF Ablation. · not yet recruiting
NCT07112716 — SVC-isolation in Redo-AF Ablation With Isolated PV · NA · not yet recruiting
NCT07402798 — Anesthetic Safety of High-Frequency, Very-Low Tidal Volume Ventilation With Controlled Peak Pressure During Atrial Fibri · completed
NCT07330791 — Right Phrenic Nerve Localization on CT for Ablation · completed
NCT06730607 — Image-Based Prediction of Ventricular Tachycardias in Post-Myocarditis Patients: an International Multicenter Case-contr · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04394923 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centro Medico Teknon
Last refreshed: 19 January 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04394923.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing