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NCT04374214
Effect of Simvastatin as Pulpotomy Agent in Cariously Exposed Permanent Molars
NA trial testing Complete Pulpotomy using Mineral Trioxide Aggregate in Reversible Pulpitis in 56 participants. Status unknown.
30 April 2020
Quick facts
| Lead sponsor | Postgraduate Institute of Dental Sciences Rohtak |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 56 |
| Start date | 1 December 2018 |
| Primary completion | 30 April 2020 |
| Estimated completion | 30 June 2020 |
| Sites | 1 location across India |
Drugs / interventions tested
- Complete Pulpotomy using Mineral Trioxide Aggregate
- Complete Pulpotomy using Simvastain -alphatricalcium phosphate
Conditions studied
- Reversible Pulpitis — all drugs for Reversible Pulpitis →
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Who can join
Adults 15 to 40, any sex, with Reversible Pulpitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will compare the outcome of complete pulpotomy in mature permanent mandibular molars with deep carious lesions by using Mineral Trioxide Aggregate and Simvastatin -alpha tricalcium phosphate as medicament agent
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of Simvastatin on Success of Pulpotomy in Carious Permanent Molars With Symptomatic Irreversible Pulpitis: A Randomised Controlled Trial.
Gehlot S, Kumar V, Mittal S, Duhan J, et al · · 2026 · PMID 41652862 · DOI 10.1111/aej.70062
Verify or expand the search:
- PubMed search for NCT04374214
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Reversible Pulpitis
Currently open trials in the same condition.
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- NCT06433297 — Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars · NA · recruiting
- NCT07101068 — Assessment of Pain and Anxiety During Infiltration Anesthesia Using Dental Anesthesia Injector Versus Conventional Syrin · NA · recruiting
Other Postgraduate Institute of Dental Sciences Rohtak trials
Trials by the same sponsor.
- NCT07412067 — Healing of Apicomarginal Defects Using Autograft or Allograft With Collagen Membrane · NA · not yet recruiting
- NCT07381595 — Role of Subgingival Instrumentation in Oral Lichen Planus · NA · not yet recruiting
- NCT07300124 — Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis · NA · not yet recruiting
- NCT07506135 — Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars. · NA · completed
- NCT07179835 — To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04374214 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Postgraduate Institute of Dental Sciences Rohtak
- Last refreshed: 5 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04374214.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing