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NCT04371276

Seroepidemiology of Viral Hepatitis in Hong Kong

Completed Last updated 8 February 2023
What this trial tests

trial testing No intervention in Viral Hepatitis in 2,888 participants. Completed in 31 May 2022.

Timeline
1 September 2018
Primary endpoint
31 December 2021
31 May 2022

Quick facts

Lead sponsorChinese University of Hong Kong
StatusCompleted
Study typeOBSERVATIONAL
Enrollment2,888
Start date1 September 2018
Primary completion31 December 2021
Estimated completion31 May 2022
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Chinese University of Hong Kong

Who can join

Eligibility, any sex, with Viral Hepatitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Immunisation policies have strong influences on the epidemiology of hepatitis A and B infection. In Hong Kong, vaccines against both viruses have been available through different channels and programmes in the past 3 decades. To evaluate the changes in the prevalence of hepatitis A and B in the general population, a seroepidemiology study is conducted involving a prospective cross-sectional survey followed for serology testing. Eligible members of 1327 spatially random households would be invited to join the study by completing a questionnaire and providing blood samples, either by dried blood spots or venesection, for determining the presence of antigen and/or antibody against hepatitis B, as well as antibody against hepatitis A. The main measures comprise a set of metrics on the prevalence of hepatitis A and B. Analysis would be conducted to examine the association of risk factors with the tested markers and describe the attitudes towards viral hepatitis vaccination. The results would allow us to understand the transmission potential of hepatitis A and B in the community would be influenced by the changing disease epidemiology and coverage of vaccination, which inform the development of new vaccination strategies in Hong Kong

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Seroepidemiology of hepatitis A and B in the general population in Hong Kong: protocol of a cross-sectional survey using spatial sampling in a highly urbanised city.
    Poon CM, Chan DP, Lee SS, Wong NS. · · 2021 · cited 5× · PMID 33753433 · DOI 10.1136/bmjopen-2020-042065

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Other trials of No intervention

Trials testing the same drug.

Other recruiting trials for Viral Hepatitis

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Other Chinese University of Hong Kong trials

Trials by the same sponsor.

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