NCT04353960 (AK-OCR) is a clinical trial of electrocardiograph in Bradycardia, sponsored by Alaska Blind Child Discovery.

Who is sponsoring NCT04353960?

NCT04353960 is sponsored by Alaska Blind Child Discovery.

What drugs are being tested in NCT04353960?

Interventions in NCT04353960: electrocardiograph.

What condition does NCT04353960 study?

NCT04353960 studies Bradycardia, Strabismus.

Is NCT04353960 still recruiting?

NCT04353960 is currently recruiting now. Last updated 31 July 2024.

Last reviewed 2024-07-31 · How we verify

NCT04353960: AK-OCR

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Alaska Oculocardiac Reflex Study

Recruiting now Last updated 31 July 2024

What this trial tests

trial testing electrocardiograph in Bradycardia in 4,000 participants. Currently enrolling.

Timeline

1 September 1992

Primary endpoint
31 December 2035

31 December 2035

Quick facts

Lead sponsor	Alaska Blind Child Discovery
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	4,000
Start date	1 September 1992
Primary completion	31 December 2035
Estimated completion	31 December 2035
Sites	1 location across United States

Drugs / interventions tested

electrocardiograph

Conditions studied

Bradycardia — all drugs for Bradycardia →
Strabismus — all drugs for Strabismus →

Sponsor

Alaska Blind Child Discovery

Who can join

Adults 1 Month to 100, any sex, with Bradycardia or Strabismus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Observation study monitoring vital signs and anesthetic variables particularly heart rate during prospective, ocular manipulation and specifically uniform tension on extra ocular muscles during strabismus surgery. \*IRB approval from 1992 covered in letter from then IRB chair Dr. Judith Whitcomb, Anchorage, Alaska (letter 10/2020).\*

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

The Oculocardiac Reflex: A Review.
Arnold RW. · · 2021 · cited 27× · PMID 34194223 · DOI 10.2147/opth.s317447
Anesthetic Impacts on the Oculocardiac Reflex: Evidence from a Large, Observational Study.
Arnold RW, Jansen S, Seelig JC, Glasionov M, et al · · 2021 · cited 8× · PMID 33716499 · DOI 10.2147/opth.s300860
Oculocardiac Reflex During ROP Exams.
Schumacher AC, Ball ML, Arnold AW, Grendahl RL, et al · · 2020 · cited 8× · PMID 33324032 · DOI 10.2147/opth.s288043
The Impact of Re-Operation, Relatives and Race on the Oculocardiac Reflex During Strabismus Surgery.
Arnold RW, Rinner AR, Arnold AW, Beerle BJ. · · 2020 · cited 8× · PMID 33299298 · DOI 10.2147/opth.s288578
Oculocardiac Reflex During Strabismus Surgery: Conjunctival Incision versus Standardized Rectus Muscle Traction.
Reicks BJ, Bond T, Lunoe L, Glasionov M, et al · · 2026 · PMID 42137523 · DOI 10.2147/opth.s590686

Verify or expand the search:

Other trials of electrocardiograph

Trials testing the same drug.

NCT06330987 — Fetal Autonomic Nervous sysTem Evaluation · unknown

Other recruiting trials for Bradycardia

Currently open trials in the same condition.

NCT07209852 — Safety, Performance, and Clinical Benefit of Pacing the Left Bundle Branch Area - Post-Market Clinical Follow-up · recruiting
NCT07254013 — Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution · NA · recruiting
NCT07166614 — Dexmedetomidine vs Propofol in High-Risk ERCP Patients · NA · recruiting
NCT07585799 — Permanent Conduction System Pacing Versus Atrioventricular Management for Patients With Wide QRS and Patent AV Conductio · NA · recruiting
NCT07217392 — Left Bundle Branch Area Pacing (LBBAP) PMCF Study · NA · recruiting

Other Alaska Blind Child Discovery trials

Trials by the same sponsor.

NCT06165705 — Treating Amblyopia With CureSight · NA · unknown
NCT04249505 — Refractive Accuracy of "2WIN" and Portable Autorefractors · completed
NCT04195711 — Comparative Validation of "Blinq" and "2WIN" Vision Screeners · completed
NCT04297969 — Hyperopia Detection GCK With Glow Fixation · completed
NCT04068129 — Enhanced Housing Photoscreeners 2WIN and GoCheckKids Compared in Burma and Alaska · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04353960 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Alaska Blind Child Discovery
Last refreshed: 31 July 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04353960.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing