NCT04353362 is a Phase 4 clinical trial of Ofloxacin in Amoxicillin, sponsored by Istanbul Medipol University Hospital.

Who is sponsoring NCT04353362?

NCT04353362 is sponsored by Istanbul Medipol University Hospital.

What drugs are being tested in NCT04353362?

Interventions in NCT04353362: Ofloxacin, Amoxicillin, Metronidazole.

What condition does NCT04353362 study?

NCT04353362 studies Amoxicillin, Metronidazole, Ofloxacin, Periodontitis, Root Planing.

Is NCT04353362 still recruiting?

NCT04353362 is currently completed. Last updated 20 April 2020.

Last reviewed 2020-04-20 · How we verify

NCT04353362

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Alternative Antibiotic Regimen in Periodontitis Treatment

Completed Phase 4 Last updated 20 April 2020

What this trial tests

Phase 4 trial testing Ofloxacin in Amoxicillin in 74 participants. Completed in 10 March 2020.

Timeline

1 April 2017

Primary endpoint
2 January 2020

10 March 2020

Quick facts

Lead sponsor	Istanbul Medipol University Hospital
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	74
Start date	1 April 2017
Primary completion	2 January 2020
Estimated completion	10 March 2020
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Ofloxacin (OFLOXACIN) — full drug profile →
Amoxicillin (amoxicillin) — full drug profile →
Metronidazole (METRONIDAZOLE) — full drug profile →

Conditions studied

Amoxicillin — all drugs for Amoxicillin →
Metronidazole — all drugs for Metronidazole →
Ofloxacin — all drugs for Ofloxacin →
Periodontitis — all drugs for Periodontitis →

Sponsor

Istanbul Medipol University Hospital

Who can join

Adults 20 to 40, any sex, with Amoxicillin or Metronidazole. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Context and Aims: Several studies have demonstrated an association between obesity, periodontitis, and exercise. This study aimed to investigate the effects of regular exercise on obese women with periodontal disease, using serum, saliva, and gingival crevicular fluid (GCF) samples. Settings and Design: A before-after study design was adopted to evaluate the effects of 12 weeks of regular exercise on obese women grouped according to periodontal status, without a control group (no exercise). Methods and Material: The study sample comprised fifteen patients without periodontitis (NP group) and 10 patients with chronic periodontitis (CP group), from whom periodontal parameters were measured and serum, saliva, and GCF samples were collected. Body mass index (BMI), anthropometric measurements, somatotype-motoric tests, and maximal oxygen consumption (VO2max) were recorded at baseline and after exercise. Statistical analysis used: MedCalc was used for statistical analysis.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Ofloxacin

Trials testing the same drug.

NCT04005079 — Pilocarpine After Combined Cataract/Trabectome Surgery · Phase 3 · withdrawn
NCT02373137 — Descemet Endothelial Thickness Comparison Trial · Phase 4 · unknown

Other Istanbul Medipol University Hospital trials

Trials by the same sponsor.

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NCT07575477 — Comparison Of Early Mobilization And Electrical Stimulation On Functional Recovery After Lumbar Disc Herniation Surgery · NA · not yet recruiting
NCT07525115 — Effects of Proprioceptive Neuromuscular Facilitation-Based Lower Extremity Training on Balance, Gait, and Functional Ind · NA · not yet recruiting
NCT07467278 — Low-FODMAP Diet and Intestinal Permeability in Patients With Irritable Bowel Syndrome · NA · not yet recruiting
NCT07468864 — Validity of the Turkish Situational Vertigo Questionnaire · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04353362 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istanbul Medipol University Hospital
Last refreshed: 20 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04353362.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing