NCT04352062 is a NA clinical trial of Melatonin in Melatonin Deficiency, sponsored by Medical University of Lodz.

Who is sponsoring NCT04352062?

NCT04352062 is sponsored by Medical University of Lodz.

What drugs are being tested in NCT04352062?

Interventions in NCT04352062: Melatonin, placebo, Pantoprazole 40mg, Amoxicillin, Levofloxacin 500mg.

What condition does NCT04352062 study?

NCT04352062 studies Melatonin Deficiency.

Is NCT04352062 still recruiting?

NCT04352062 is currently completed. Last updated 17 April 2020.

Last reviewed 2020-04-17 · How we verify

NCT04352062

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia

Completed NA Last updated 17 April 2020

What this trial tests

NA trial testing Melatonin in Melatonin Deficiency in 152 participants. Completed in 26 October 2018.

Timeline

9 January 2011

Primary endpoint
26 October 2018

26 October 2018

Quick facts

Lead sponsor	Medical University of Lodz
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	152
Start date	9 January 2011
Primary completion	26 October 2018
Estimated completion	26 October 2018
Sites	1 location across Poland

Drugs / interventions tested

Melatonin (MELATONIN) — full drug profile →
placebo
Pantoprazole 40mg — full drug profile →
Amoxicillin (amoxicillin) — full drug profile →
Levofloxacin 500mg — full drug profile →

Conditions studied

Melatonin Deficiency — all drugs for Melatonin Deficiency →

Sponsor

Medical University of Lodz

Who can join

Adults 49 to 64, female only, with Melatonin Deficiency. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: The aim of the study was to assess the role of melatonin in chronic dyspepsia in this group of women, with consideration of Helicobacter infection. Methods: The study comprised 152 subjects Including 30 healthy women (group I), 60 women with asymptomatic H.pylori infection (group II), and 64 women H. pylori infected with chronic dyspepsia(group III). Endoscopic examination, histological assessment of gastric end duodenal mucosa, urease breath test(UBT-13C), and serum levels of 17-β-estradiol, follicle stimulating hormone, melatonin and urinary concentration of 6-sulfatoxymelatonin were determined by immunoenzymatic method. In group III - 14-day antibacterial treatment was introduced with pantoprazole, amoxicillin and levofloxacin. Afterward, in 32 women was administered placebo(group IIIa), and in 32 women (group IIIb) melatonin at a dose 1 m/morning and 3 mg/at bedtime, for six months.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia.
Chojnacki C, Mędrek-Socha M, Konrad P, Chojnacki J, et al · · 2020 · cited 7× · PMID 33243209 · DOI 10.1186/s12905-020-01117-z
The value of melatonin supplementation in postmenopausal women with Helicobacter pylori-associated dyspepsia
Chojnacki C, Mędrek-Socha M, Konrad P, Chojnacki J, et al · · 2020 · DOI 10.21203/rs.3.rs-31148/v3

Verify or expand the search:

Other trials of Melatonin

Trials testing the same drug.

NCT07221968 — Melatonin for the Treatment of DEE-SWAS · Phase 2 · not yet recruiting
NCT07503600 — The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections · Phase 3 · not yet recruiting
NCT07375342 — Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric · NA · enrolling by invitation
NCT07305350 — EFFICACY OF MELATONIN IN MANAGEMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE) IN NEONATES · Phase 2 · active not recruiting
NCT07096635 — Oral Melatonin With Intra Articular Analgesia on Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction · NA · not yet recruiting

Other Medical University of Lodz trials

Trials by the same sponsor.

NCT07391969 — Evaluation of SaCo VLMA for General Anesthesia for Laparoscopic Procedures · NA · not yet recruiting
NCT06453317 — Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis · Phase 2 · recruiting
NCT06850597 — Efficacy and Safety of Dimethyl Fumarate Among Patients with Mild Cognitive Impairment and Dementia Due to Alzheimer's D · Phase 2 · recruiting
NCT06917300 — Virtual Reality as a Digital Premed to Alleviate Pain and Anxiety Preoperatively in Patients Undergoing Spine Surgery · NA · recruiting
NCT06391216 — The Effect of Probiotic Supplementation on Mental Health in Healthy Volunteers · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04352062 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Medical University of Lodz
Last refreshed: 17 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04352062.

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