NCT04346433 is a NA clinical trial of Restricted Sleep in Obesity, Childhood, sponsored by University of Alabama at Birmingham.

Who is sponsoring NCT04346433?

NCT04346433 is sponsored by University of Alabama at Birmingham.

What drugs are being tested in NCT04346433?

Interventions in NCT04346433: Restricted Sleep, Adequate Sleep.

What condition does NCT04346433 study?

NCT04346433 studies Obesity, Childhood, Overweight, Childhood.

Is NCT04346433 still recruiting?

NCT04346433 is currently completed. Last updated 13 July 2023.

Last reviewed 2023-07-13 · How we verify

NCT04346433

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function

Completed NA Last updated 13 July 2023

What this trial tests

NA trial testing Restricted Sleep in Obesity, Childhood in 61 participants. Completed in 1 October 2022.

Timeline

1 September 2020

Primary endpoint
1 October 2022

1 October 2022

Quick facts

Lead sponsor	University of Alabama at Birmingham
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	single
Primary purpose	basic science
Enrollment	61
Start date	1 September 2020
Primary completion	1 October 2022
Estimated completion	1 October 2022
Sites	1 location across United States

Drugs / interventions tested

Restricted Sleep
Adequate Sleep

Conditions studied

Obesity, Childhood — all drugs for Obesity, Childhood →
Overweight, Childhood — all drugs for Overweight, Childhood →

Sponsor

University of Alabama at Birmingham

Who can join

Adults 14 to 19, any sex, with Obesity, Childhood or Overweight, Childhood. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators aim to assess the relationship between overweight/obesity and decreased cognitive function in adolescents. While this relationship has been seen in past literature, the causal mechanisms are still unclear. Thus, the present study will assess sleep and stigma as possible moderators. As sleep is related to both weight and cognitive abilities it may be an important factor in the relationship between these two variables. Further, people with overweight/obesity have higher risk for stigma experiences which may increase inflammation through chronic stress and elevated cortisol. Because inflammation is theorized to play a role in the relationship between elevated BMI and decreased cognitive function, stigma may be an important moderator. 60 adolescent participants will complete two sleep conditions (adequate and restricted) in a randomized order, each followed by a lab visit during which participants will complete a short cognitive battery. At these visits, participants will also be given a self serve breakfast with a variety of whole and processed food options to further evaluate the relationship between overweight/obesity, sleep, nutritional intake, and cognitive function.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Effect of Sleep Restriction on Adolescent Cognition by Adiposity: A Randomized Crossover Trial.
Stager LM, Watson CS, Cook EW, Fobian AD. · · 2024 · cited 3× · PMID 38767872 · DOI 10.1001/jamaneurol.2024.1332
Adolescent sleep restriction, macronutrient consumption, and self-reported hunger: A randomized clinical trial.
Stager LM, Maruvada A, Morgan C, Taha R, et al · · 2026 · PMID 41825204 · DOI 10.1016/j.clnu.2026.106606

Verify or expand the search:

Other recruiting trials for Obesity, Childhood

Currently open trials in the same condition.

NCT06810557 — Brief Behavioral Sleep Intervention for Obesity Prevention in Primary Care · NA · recruiting
NCT06892483 — Breastmilk in Response to a Bout of Exercise · recruiting
NCT06464497 — Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity · NA · recruiting
NCT06847373 — Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity · NA · recruiting
NCT06579079 — Improving Participation in Universal School Meals (USM) · NA · active not recruiting

Other University of Alabama at Birmingham trials

Trials by the same sponsor.

NCT04922229 — Comparative Effectiveness in the Management of Irreversible Pulpitis · NA · not yet recruiting
NCT05060380 — Feasibility of a Novel Resistance Exercise in Individuals With Osteoporosis · NA · withdrawn
NCT04768777 — Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple Sclerosis · NA · not yet recruiting
NCT06320951 — VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine · Phase 2 · not yet recruiting
NCT07564934 — Leveraging Extended Reality Exergaming and Telehealth to Improve Physical Activity and Health in Children With Disabilit · Phase 2 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04346433 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Alabama at Birmingham
Last refreshed: 13 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04346433.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing