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NCT04346160
A Study to Assess the Virus RNA, and miRNA Levels Related to Viral Infection, and Inflammatory Response in Tears of Patients Affected by COVID-19 Disease
trial testing Schirmer Test I in COVID in 25 participants. Status unknown.
30 April 2020
Quick facts
| Lead sponsor | G. d'Annunzio University |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 25 |
| Start date | 14 April 2020 |
| Primary completion | 30 April 2020 |
| Estimated completion | 30 April 2020 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Schirmer Test I
Conditions studied
- COVID — all drugs for COVID →
- Conjunctivitis — all drugs for Conjunctivitis →
Sponsor
G. d'Annunzio University
Who can join
18 and older, any sex, with COVID or Conjunctivitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to assess the virus RNA, and miRNA levels related to viral infection, and inflammatory response in tears of hospitalized patients with a diagnosis of COVID-19 with and without conjunctivitis and to correlate them with clinical condition. Tears will be collected by using Schirmer Test I, a non invasive painless test which can be performed at the patient's bed. Tears will be collected on the graduated paper strips pulling the lower lid gently downward for 5 minutes. Following, the strip will be placed in a 2.0 mL Eppendorf tube and stored at -80◦C (or - 20°C)
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review).
Katopodis P, Randeva HS, Spandidos DA, Saravi S, et al · · 2022 · cited 24× · PMID 34935057 · DOI 10.3892/ijmm.2021.5075
Verify or expand the search:
- PubMed search for NCT04346160
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other G. d'Annunzio University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04346160 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by G. d'Annunzio University
- Last refreshed: 20 April 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04346160.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing