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NCT04343898: STOP-COVID
Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19
Completed
Last updated 9 August 2023
What this trial tests
trial testing No intervention in Coronavirus Infection in 5,154 participants. Completed in 1 July 2023.
Timeline
1 April 2020
Primary endpoint
1 August 2020
1 August 2020
1 July 2023
Quick facts
| Lead sponsor | Brigham and Women's Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 5,154 |
| Start date | 1 April 2020 |
| Primary completion | 1 August 2020 |
| Estimated completion | 1 July 2023 |
| Sites | 1 location across United States |
Drugs / interventions tested
- No intervention
Conditions studied
- Coronavirus Infection — all drugs for Coronavirus Infection →
Sponsor
Brigham and Women's Hospital
Who can join
18 and older, any sex, with Coronavirus Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Multicenter observational/registry study of the clinical features and outcomes of critically ill patients with COVID-19.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
AKI Treated with Renal Replacement Therapy in Critically Ill Patients with COVID-19.
Gupta S, Coca SG, Chan L, Melamed ML, et al · · 2021 · cited 215× · PMID 33067383 · DOI 10.1681/asn.2020060897 -
In-hospital cardiac arrest in critically ill patients with covid-19: multicenter cohort study.
Hayek SS, Brenner SK, Azam TU, Shadid HR, et al · · 2020 · cited 102× · PMID 32998872 · DOI 10.1136/bmj.m3513 -
Outcomes of critically ill solid organ transplant patients with COVID-19 in the United States.
Molnar MZ, Bhalla A, Azhar A, Tsujita M, et al · · 2020 · cited 83× · PMID 32844546 · DOI 10.1111/ajt.16280 -
Implementation of the trial emulation approach in medical research: a scoping review.
Scola G, Chis Ster A, Bean D, Pareek N, et al · · 2023 · cited 25× · PMID 37587484 · DOI 10.1186/s12874-023-02000-9 -
Relationship Between Preexisting Cardiovascular Disease and Death and Cardiovascular Outcomes in Critically Ill Patients With COVID-19.
Vasbinder A, Meloche C, Azam TU, Anderson E, et al · · 2022 · cited 21× · PMID 36193749 · DOI 10.1161/circoutcomes.122.008942 -
The Impact of Chronic Kidney Disease on Outcomes of Patients with COVID-19 Admitted to the Intensive Care Unit.
Brogan M, Ross MJ. · · 2022 · cited 19× · PMID 34634789 · DOI 10.1159/000519530 -
Acute Kidney Injury in the Time of COVID-19.
Chan L, Coca SG. · · 2020 · cited 12× · PMID 35372928 · DOI 10.34067/kid.0003722020 -
MUlticenter STudy of tissue plasminogen activator (alteplase) use in COVID-19 severe respiratory failure (MUST COVID): A retrospective cohort study.
Barrett CD, Moore HB, Moore EE, Benjamin Christie D, et al · · 2022 · cited 6× · PMID 35341072 · DOI 10.1002/rth2.12669
Verify or expand the search:
- PubMed search for NCT04343898
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
Data sources for this page
- Trial protocol + status: ClinicalTrials.gov NCT04343898 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Brigham and Women's Hospital
- Last refreshed: 9 August 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04343898.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing