NCT04340453

The Comparison of Hip and Knee Focused Exercises Versus Hip and Knee Focused Exercises With the Use of Blood Flow Restriction Training in Adults With Patellofemoral Pain

Completed NA Last updated 9 April 2020

What this trial tests

NA trial testing Exercise with Blood Flow restriction training in Patellofemoral Pain Syndrome in 60 participants. Completed in 29 February 2020.

Timeline

29 November 2019

Primary endpoint
21 December 2019

29 February 2020

Quick facts

Lead sponsor	European University Cyprus
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	60
Start date	29 November 2019
Primary completion	21 December 2019
Estimated completion	29 February 2020
Sites	1 location across Cyprus

Drugs / interventions tested

• Exercise with Blood Flow restriction training
• Hip and Knee Exercise Program
• stretching

Conditions studied

• Patellofemoral Pain Syndrome — all drugs for Patellofemoral Pain Syndrome →

Sponsor

European University Cyprus

Who can join

Adults 18 to 40, any sex, with Patellofemoral Pain Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hip and Knee strengthening exercises are implemented in Patellofemoral Pain (PFP) rehabilitation but exercising in high loads to achieve muscle changes in strength may lead to increased patellofemoral joint stress. Low load training with Blood Flow Restriction (BFR) may allow for exercise strength benefits to proximal and distal muscles with reduced joint stress and by promoting hypoalgesia.

The purpose of this study is to compare hip and knee focused exercises with and without BFR training in adults with PFP. The main outcome of this study is function ability which will be measured with the Kujala Anterior Knee pain Scale translated in the Greek language at four weeks post intervention and at two months follow up. Our null hypothesis is that there will be no difference between groups for primary and secondary outcomes measured at four weeks and two months post intervention.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Comparing hip and knee focused exercises versus hip and knee focused exercises with the use of blood flow restriction training in adults with patellofemoral pain.
   Constantinou A, Mamais I, Papathanasiou G, Lamnisos D, et al · · 2022 · cited 24× · PMID 34985237 · DOI 10.23736/s1973-9087.22.06691-6