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NCT07318987
EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME
NA trial testing Saphenous nerve release in Patellofemoral Pain Syndrome in 36 participants. Currently enrolling.
10 January 2026
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 10 October 2025 |
| Primary completion | 10 January 2026 |
| Estimated completion | 27 January 2026 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Saphenous nerve release
Conditions studied
- Patellofemoral Pain Syndrome — all drugs for Patellofemoral Pain Syndrome →
Sponsor
Cairo University
Who can join
Adults 18 to 35, any sex, with Patellofemoral Pain Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patellofemoral Pain Syndrome (PFPS) is a frequent cause of anterior knee pain in young, physically active individuals, especially females, and is commonly managed with quadriceps and hip-focused exercises. However, the role of neural factors has been largely overlooked. The saphenous nerve, which supplies sensation to the anteromedial knee, may become irritated or entrapped and contribute to pain and neuromuscular dysfunction in PFPS. This study suggests that manual therapy targeting the saphenous nerve could improve pain, function, and balance, providing a more holistic approach to PFPS rehabilitation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07318987
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Patellofemoral Pain Syndrome
Currently open trials in the same condition.
- NCT06913426 — Effects of Pelvic Tilt Exercises Along With Hip and Knee Focused Exercises on Patients With Patellofemoral Pain Syndrome · NA · active not recruiting
- NCT06875804 — Compressive Myofascial Release of the Vastus Lateralis on Lateral Patellar Tracking in Patellofemoral Pain Syndrome · NA · recruiting
- NCT06598618 — Comparison of IASTM and Muscle Energy Technique in Patellofemoral Pain Syndrome. · NA · recruiting
- NCT06566950 — BFR Training on Muscle Morphology · NA · recruiting
- NCT06758050 — Effect of Core Exercises on Patellofemoral Pain Syndrome · NA · recruiting
Other Cairo University trials
Trials by the same sponsor.
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- NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
- NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
- NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07318987 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 6 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07318987.
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