Last reviewed · How we verify
NCT04325087: COOL
Reduction of Trauma-induced Intrusions and Amygdala Hyperreactivity Via Non-invasive Brain Stimulation
NA trial testing iTBS in Intrusive Thoughts in 120 participants. Status unknown.
30 May 2020
Quick facts
| Lead sponsor | University Hospital, Bonn |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 120 |
| Start date | 1 July 2019 |
| Primary completion | 30 May 2020 |
| Estimated completion | 30 May 2020 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- iTBS
- Placebo iTBS
Conditions studied
- Intrusive Thoughts — all drugs for Intrusive Thoughts →
- Post Traumatic Stress Disorder — all drugs for Post Traumatic Stress Disorder →
Sponsor
University Hospital, Bonn
Who can join
Adults 18 to 45, any sex, with Intrusive Thoughts or Post Traumatic Stress Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will focus on the modulation of intrusive memories via functional magnetic resonance imaging (fMRI)-guided repetitive transcranial magnetic stimulation of the dorsolateral prefrontal cortex (dlPFC) directly after exposure to a traumatic video.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04325087
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04325087 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Bonn
- Last refreshed: 27 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04325087.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing