NCT04321109

Alveolar Ridge Preservation Using Collagen Material and Allograft

Completed NA Last updated 23 September 2022

What this trial tests

NA trial testing Allograft in Alveolar Ridge Preservation in 14 participants. Completed in 21 March 2018.

Timeline

2 June 2016

Primary endpoint
21 March 2018

21 March 2018

Quick facts

Lead sponsor	Yasmine Fouad
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	14
Start date	2 June 2016
Primary completion	21 March 2018
Estimated completion	21 March 2018

Drugs / interventions tested

• Allograft — full drug profile →
• Collagen cone

Conditions studied

• Alveolar Ridge Preservation — all drugs for Alveolar Ridge Preservation →

Sponsor

Yasmine Fouad

Who can join

Adults 20 to 40, any sex, with Alveolar Ridge Preservation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Seven Patients who need implants to replace non-restorable teeth in the esthetic zone.

Intervention Group (1): Seven extraction sockets that received the collagen matrix (Collagen cone) for alveolar ridge preservation.

Comparison Group (2): Seven extraction sockets that were treated with mineralized cortico-cancellous bone allograft for alveolar ridge preservation.

Outcome

1. Alveolar ridge preservation both in height and in width to improve implant success rate

* The height of alveolar ridge was assessed clinically using a periodontal probe.
* The width of the alveolar ridge was measured after three months after extraction using a caliper clamp.
* Changes in the width and height of alveolar bone were evaluated in merged axial and sagittal views using the I-CAT superimposition system (CBCT).

2- Evaluation of newly formed bone quality was performed by histological examination and histomorphometric analysis.

3- Immuno-histochemical staining was done using polyclonal antibody to detect (BMP-2) marker of bone formation

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.