NCT04317222 (LTeCRRT) is a NA clinical trial of eCRRT in Acute-On-Chronic Liver Failure, sponsored by Third Affiliated Hospital, Sun Yat-Sen University.

Who is sponsoring NCT04317222?

NCT04317222 is sponsored by Third Affiliated Hospital, Sun Yat-Sen University.

What drugs are being tested in NCT04317222?

Interventions in NCT04317222: eCRRT.

What condition does NCT04317222 study?

NCT04317222 studies Acute-On-Chronic Liver Failure, Hepatic Encephalopathy.

Is NCT04317222 still recruiting?

NCT04317222 is currently status unknown. Last updated 23 March 2020.

Last reviewed 2020-03-23 · How we verify

NCT04317222: LTeCRRT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Early Postoperative CRRT After Liver Transplantation in ACLF Patients With Overt HE

Status unknown NA Last updated 23 March 2020

What this trial tests

NA trial testing eCRRT in Acute-On-Chronic Liver Failure in 250 participants. Status unknown.

Timeline

1 June 2020

Primary endpoint
31 May 2022

31 August 2022

Quick facts

Lead sponsor	Third Affiliated Hospital, Sun Yat-Sen University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	250
Start date	1 June 2020
Primary completion	31 May 2022
Estimated completion	31 August 2022

Drugs / interventions tested

eCRRT

Conditions studied

Acute-On-Chronic Liver Failure — all drugs for Acute-On-Chronic Liver Failure →
Hepatic Encephalopathy — all drugs for Hepatic Encephalopathy →

Sponsor

Third Affiliated Hospital, Sun Yat-Sen University

Who can join

Adults 18 to 70, any sex, with Acute-On-Chronic Liver Failure or Hepatic Encephalopathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pretransplant hepatoencephalopathy (HE) markedly impacts recipient outcomes after liver transplantation. Intraoperative CRRT showed benefits but feasibility was much concerned. This study aims to observe the effect on consciousness recovery when initiating CRRT early in the post-transplant period in recipients with ACLF and overt HE.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Acute-On-Chronic Liver Failure

Currently open trials in the same condition.

NCT07198854 — Risk Factors Affecting MSC Efficacy in ACLF Patients · recruiting
NCT06996392 — Phase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver Failure · Phase 1 · active not recruiting
NCT06831565 — Comparison of Blood Products Required Using Two Different ROTEM Cut-offs Before Invasive Procedures in Cirrhosis and Acu · NA · recruiting
NCT06562803 — Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis · NA · recruiting
NCT06079021 — COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device · NA · recruiting

Other Third Affiliated Hospital, Sun Yat-Sen University trials

Trials by the same sponsor.

NCT07409259 — PT-MSCs Exosome Injection in the Treatment of Chronic-to-acute Liver Failure · EARLY_PHASE1 · active not recruiting
NCT07281664 — Transarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unresectable Hep · NA · not yet recruiting
NCT07338552 — Effectiveness of a Virtual Health Management Community (VHMC) for Pre-diabetes in China · NA · not yet recruiting
NCT07354997 — Establishing a Virtual Health Community Management Model for Pre-Diabetes Patients · NA · completed
NCT07253233 — Treatment of Spinal Cord Injury Using Autologous Concentrated Growth Factors · EARLY_PHASE1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04317222 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Third Affiliated Hospital, Sun Yat-Sen University
Last refreshed: 23 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04317222.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing