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NCT04311814
The Valsalva Urethral Profile : a Measure to Assess Stress Urinary Incontinence
NA trial testing Maximum urethral closure pressure during Valsalva (v-MUCP) in Stress Urinary Incontinence in 695 participants. Completed in 20 December 2019.
25 September 2019
Quick facts
| Lead sponsor | Poissy-Saint Germain Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 695 |
| Start date | 15 February 2016 |
| Primary completion | 25 September 2019 |
| Estimated completion | 20 December 2019 |
Drugs / interventions tested
- Maximum urethral closure pressure during Valsalva (v-MUCP)
Conditions studied
- Stress Urinary Incontinence — all drugs for Stress Urinary Incontinence →
Sponsor
Poissy-Saint Germain Hospital
Who can join
18 and older, female only, with Stress Urinary Incontinence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Clinical and paraclinical appraisal of stress urinary incontinence (SUI) is mainly based on the assessment of pelvic floor muscles (PFM) contraction and urethral mobility, the measurement of the maximum urethral closure pressure (MUCP) at rest by urethral pressure profilometry (UPP) and the measurement of the Valsalva leak point pressure (VLPP). Currently, MUCP and VLPP cannot be used for diagnosing SUI because they appear to be moderately correlated with the severity of SUI. The lack of a specific SUI biomarker could be the explanation for the poor predictive value of urodynamics and the ongoing debate on whether urodynamic testing before surgery has benefits. Our main objective was to study the value of a new urodynamic parameter in the diagnosis of female SUI: the Valsalva urethral profile (VUP)
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04311814
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Poissy-Saint Germain Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04311814 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Poissy-Saint Germain Hospital
- Last refreshed: 17 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04311814.
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