Last reviewed · How we verify
NCT06924450: MOTOT
Effect of Modified Mesh on Surgical Success in Transobturator Tape Surgery
NA trial testing 1.2 cm Mesh TOT in Stress Urinary Incontinence in 106 participants. Currently enrolling.
12 November 2025
Quick facts
| Lead sponsor | Izzet Celegen |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 106 |
| Start date | 12 May 2025 |
| Primary completion | 12 November 2025 |
| Estimated completion | 12 November 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- 1.2 cm Mesh TOT
- 1.0 cm Mesh TOT
Conditions studied
- Stress Urinary Incontinence — all drugs for Stress Urinary Incontinence →
- Female Urinary Incontinence — all drugs for Female Urinary Incontinence →
- Pelvic Floor Dysfunction — all drugs for Pelvic Floor Dysfunction →
Sponsor
Izzet Celegen
Who can join
18 and older, female only, with Stress Urinary Incontinence or Female Urinary Incontinence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is a single-blind, randomized controlled trial evaluating whether changing the width of the surgical tape (mesh) used in transobturator tape (TOT) surgery improves treatment results in women with stress urinary incontinence (SUI). Two mesh widths are being compared: a 1.2 cm mesh (new method) and a 1.0 cm mesh (standard method). The main goal is to find out if the wider mesh leads to better urinary control and fewer complications. Participants will be followed for one year to measure cure rates, symptom improvement, and satisfaction.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06924450
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Stress Urinary Incontinence
Currently open trials in the same condition.
- NCT06706362 — Assessing the Utility of Prophylactic Antibiotics at Time of Urethral Bulking Using Bulkamid (Bulkamid Study) · Phase 4 · recruiting
- NCT06840093 — Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial · NA · recruiting
- NCT06111209 — The Anabolic Effect of Testosterone on Pelvic Floor Muscles · Phase 2 · recruiting
- NCT06731985 — The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes. · recruiting
- NCT06126757 — PelviSense, an Innovative, Non-invasive, Biofeedback Device for the Treatment of Stress Urinary Incontinence in Women · NA · active not recruiting
Other Izzet Celegen trials
Trials by the same sponsor.
- NCT06245811 — Inflammation Markers in Hyperemesis Gravidarum · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06924450 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Izzet Celegen
- Last refreshed: 11 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06924450.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing