NCT04310683 is a NA clinical trial of natural cycle for endometrium preparation in Pre-Eclampsia, sponsored by Women's Hospital School Of Medicine Zhejiang University.

Who is sponsoring NCT04310683?

NCT04310683 is sponsored by Women's Hospital School Of Medicine Zhejiang University.

What drugs are being tested in NCT04310683?

Interventions in NCT04310683: natural cycle for endometrium preparation, hormone replaced cycle for endometrium preparation.

What condition does NCT04310683 study?

NCT04310683 studies Pre-Eclampsia.

Is NCT04310683 still recruiting?

NCT04310683 is currently status unknown. Last updated 17 March 2020.

Last reviewed 2020-03-17 · How we verify

NCT04310683

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Natural Cycle or Stimulated Cycle Versus Hormone Replaced Cycle for Pre-eclampsia Rate

Status unknown NA Last updated 17 March 2020

What this trial tests

NA trial testing natural cycle for endometrium preparation in Pre-Eclampsia in 840 participants. Status unknown.

Timeline

10 November 2020

Primary endpoint
10 December 2021

10 March 2022

Quick facts

Lead sponsor	Women's Hospital School Of Medicine Zhejiang University
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	840
Start date	10 November 2020
Primary completion	10 December 2021
Estimated completion	10 March 2022

Drugs / interventions tested

natural cycle for endometrium preparation
hormone replaced cycle for endometrium preparation

Conditions studied

Pre-Eclampsia — all drugs for Pre-Eclampsia →

Sponsor

Women's Hospital School Of Medicine Zhejiang University

Who can join

Adults 18 to 45, female only, with Pre-Eclampsia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Recent sutdies indicate that the existence of corpus lutein in the ovary is a key point to prevent preeclampsia, and patients undergoing FET with hormone replaced cycle have no corpus lutein and the absence of corpus lutein significantly increases the risk of preeclampsia in these patients. We aim to conduct a single center randomized trial study to compare the preeclampsia rate between the natural cycle and the hormone replaced cycle in patients undergoing FET.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Natural ovulation versus programmed regimens before frozen embryo transfer in ovulatory women: multicentre, randomised clinical trial.
Wei D, Qin Y, Sun Y, Yan J, et al · · 2026 · PMID 41565309 · DOI 10.1136/bmj-2025-087045

Verify or expand the search:

Other recruiting trials for Pre-Eclampsia

Currently open trials in the same condition.

NCT07245056 — Fetal Fornix and Hippocampus in Pregnant Women With Early-Onset Preeclampsia · NA · recruiting
NCT07187596 — Mortality Outcome of Controlled Hypertension · active not recruiting
NCT06893510 — Virtual Reality-Based and Face-to-Face Relaxation Programs in Pregnant Women With Preeclampsia · NA · recruiting
NCT06122220 — Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia. · NA · recruiting
NCT06779916 — Autophagy/Apoptosis Balance in Placental Vascular Pathologies · recruiting

Other Women's Hospital School Of Medicine Zhejiang University trials

Trials by the same sponsor.

NCT07369986 — Immunotherapy for Surgery Avoidance in Vulnerable dMMR Endometrial Cancer · Phase 2 · not yet recruiting
NCT07244965 — Neoadjuvant Ivonescimab Plus Chemotherapy Followed by Concurrent Chemoradiotherapy in High-Risk Locally Advanced Cervica · Phase 2 · not yet recruiting
NCT06561308 — Clinical Efficacy Study of PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Advanced Endometrial Cancer · Phase 2 · recruiting
NCT07106853 — Prenatal Cell-free DNA Screening in Pregnancies With Diverse Genetic Risk Profiles Utilizing Targeted and Whole-exome Se · not yet recruiting
NCT07082530 — A RCT of Labor Induction at 39 Weeks in Low - Risk Women in China · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04310683 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Women's Hospital School Of Medicine Zhejiang University
Last refreshed: 17 March 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04310683.

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