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NCT04305756
Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery
NA trial testing Enoxaparin in Thromboembolism in 146 participants. Completed in 15 December 2021.
15 December 2021
Quick facts
| Lead sponsor | University of Utah |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 146 |
| Start date | 12 June 2020 |
| Primary completion | 15 December 2021 |
| Estimated completion | 15 December 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Enoxaparin — full drug profile →
Conditions studied
- Thromboembolism — all drugs for Thromboembolism →
- Postpartum DVT — all drugs for Postpartum DVT →
- Thrombosis — all drugs for Thrombosis →
Sponsor
University of Utah
Who can join
Adults 18 to 55, female only, with Thromboembolism or Postpartum DVT. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to evaluate the efficacy of two dosing regimens of low molecular weight heparin (LMWH) to reach prophylactic anti-factor Xa levels in post-cesarean delivery women. Half of participants will receive a fixed dose of LMWH, while the other half will receive a weight-based dose. The hypothesis is that the use of a weight-based dose will result in more women reaching prophylactic levels.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period.
Middleton P, Shepherd E, Gomersall JC. · · 2021 · cited 43× · PMID 33779986 · DOI 10.1002/14651858.cd001689.pub4 -
Weight-Based Compared With Fixed-Dose Enoxaparin Prophylaxis After Cesarean Delivery: A Randomized Controlled Trial.
Bruno AM, Allshouse AA, Campbell HM, Branch DW, et al · · 2022 · cited 14× · PMID 36075079 · DOI 10.1097/aog.0000000000004937
Verify or expand the search:
- PubMed search for NCT04305756
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04305756 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Utah
- Last refreshed: 28 January 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04305756.
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