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NCT04305756

Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery

Completed NA Last updated 28 January 2022
What this trial tests

NA trial testing Enoxaparin in Thromboembolism in 146 participants. Completed in 15 December 2021.

Timeline
12 June 2020
Primary endpoint
15 December 2021
15 December 2021

Quick facts

Lead sponsorUniversity of Utah
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposeprevention
Enrollment146
Start date12 June 2020
Primary completion15 December 2021
Estimated completion15 December 2021
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

University of Utah

Who can join

Adults 18 to 55, female only, with Thromboembolism or Postpartum DVT. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to evaluate the efficacy of two dosing regimens of low molecular weight heparin (LMWH) to reach prophylactic anti-factor Xa levels in post-cesarean delivery women. Half of participants will receive a fixed dose of LMWH, while the other half will receive a weight-based dose. The hypothesis is that the use of a weight-based dose will result in more women reaching prophylactic levels.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period.
    Middleton P, Shepherd E, Gomersall JC. · · 2021 · cited 43× · PMID 33779986 · DOI 10.1002/14651858.cd001689.pub4
  2. Weight-Based Compared With Fixed-Dose Enoxaparin Prophylaxis After Cesarean Delivery: A Randomized Controlled Trial.
    Bruno AM, Allshouse AA, Campbell HM, Branch DW, et al · · 2022 · cited 14× · PMID 36075079 · DOI 10.1097/aog.0000000000004937

Verify or expand the search:

Other trials of Enoxaparin

Trials testing the same drug.

Other recruiting trials for Thromboembolism

Currently open trials in the same condition.

Other University of Utah trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04305756.

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