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NCT04305379: BLANKET
Augmented BLAdder NecK rEconstruction Trial for Improved Urinary Function After Radical Prostatectomy
NA trial testing Augmented Bladder Neck Reconstruction in Prostate Cancer in 31 participants. Terminated before completion.
1 March 2021
Quick facts
| Lead sponsor | Johns Hopkins University |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 31 |
| Start date | 16 January 2020 |
| Primary completion | 1 March 2021 |
| Estimated completion | 1 March 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Augmented Bladder Neck Reconstruction
- Standard Bladder Neck Reconstruction
Conditions studied
- Prostate Cancer — all drugs for Prostate Cancer →
- Urinary Incontinence — all drugs for Urinary Incontinence →
- Surgery — all drugs for Surgery →
Sponsor
Johns Hopkins University
Who can join
Adults 40 to 70, male only, with Prostate Cancer or Urinary Incontinence. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators are conducting a prospective, randomized trial to investigate whether patients randomized to receive an augmented bladder neck reconstruction (aBNR) at the time of robotic-assisted laparoscopic prostatectomy experience improved urinary function post-operatively compared to patients who undergo prostatectomy with a standard BNR. An aBNR here consists of the autologous medial umbilical ligament sling as well as a bladder neck intussusception stitch. The standard BNR group will receive the intussusception stitch only.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04305379
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04305379 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Johns Hopkins University
- Last refreshed: 17 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04305379.
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